PMID: 8540505Dec 1, 1995

The surgeon's role in the treatment of chronic intestinal pseudoobstruction

The American Journal of Gastroenterology
M M MurrM Camilleri

Abstract

The surgeon's role in the treatment of patients with chronic intestinal pseudoobstruction (CIP) is under-appreciated. Our aim was to determine the effects of operative treatment on symptomatic relief of CIP. Records of all 21 patients who underwent surgery for CIP from 1980 to 1990 were reviewed. CIP was diagnosed by a combination of manometric, radiological, and/or histological examinations. Six of the nine patients who underwent resection or bypass of presumably localized disease are currently maintained on oral intake; one patient with multiple sclerosis who cannot eat is fed via a gastrostomy tube. Enterostomy tube(s) were placed in the other 12 patients; four no longer use the enterostomy tube(s), and eight rely on these decompressive tube enterostomies for symptomatic relief. After operative treatment, hospital readmissions decreased from a mean of 0.5 to 0.1 admission/year. All 19 patients currently alive report improved quality of life. Selective and directed operative treatment of patients with CIP can result in therapeutic and palliative benefits. The surgeon should have an active role in the evaluation and possible treatment of patients with CIP.

Related Concepts

Tonometry
Enterostomy (Morphologic Abnormality)
Physician's Role
Visceral Myopathy
Intestinal Pseudo-Obstruction
MS gene
Intestines
Relapse
Multiple Sclerosis
Client Satisfaction

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Synapse Loss as Therapeutic Target in MS

As we age, the number of synapses present in the human brain starts to decline, but in neurodegenerative diseases this occurs at an accelerated rate. In MS, it has been shown that there is a reduction in synaptic density, which presents a potential target for treatment. Here is the latest research on synapse loss as a therapeutic target in MS.

Artificial Intelligence in Cardiac Imaging

Artificial intelligence (ai) techniques are increasingly applied to cardiovascular (cv) medicine in cardiac imaging analysis. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

Social Learning

Social learning involves learning new behaviors through observation, imitation and modeling. Follow this feed to stay up to date on the latest research.

Cell Atlas of the Human Eye

Constructing a cell atlas of the human eye will require transcriptomic and histologic analysis over the lifespan. This understanding will aid in the study of development and disease. Find the latest research pertaining to the Cell Atlas of the Human Eye here.

Single Cell Chromatin Profiling

Techniques like ATAC-seq and CUT&Tag have the potential to allow single cell profiling of chromatin accessibility, histones, and TFs. This will provide novel insight into cellular heterogeneity and cell states. Discover the latest research on single cell chromatin profiling here.

Genetic Screens in iPSC-derived Brain Cells

Genetic screening is a critical tool that can be employed to define and understand gene function and interaction. This feed focuses on genetic screens conducted using induced pluripotent stem cell (iPSC)-derived brain cells.

Related Papers

São Paulo Medical Journal = Revista Paulista De Medicina
Carlos Renato Dos Reis LemosJosé Joaquim Ribeiro da Rocha
Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society
F AhlforsH Abrahamsson
© 2020 Meta ULC. All rights reserved