The surgical option for gastroesophageal reflux disease

The American Journal of Medicine
R A HinderK R DeVault

Abstract

Gastroesophageal reflux disease is a common condition. Most patients can be managed with medications, but patients with refractory disease, particularly those with an incompetent lower esophageal sphincter, should be referred for surgery. The open Nissen fundoplication cures >90% of patients of their symptoms. The laparoscopic approach was first applied for patients with gastroesophageal reflux disease in 1991, and since then numerous reports evaluating the early experience with this technique have been published with results similar to the open procedure. Over the last 5 years, 595 laparoscopic antireflux procedures have been performed by us. There was 1 mortality due to an unrecognized duodenal perforation. Splenic injury did not occur compared to an incidence of up to 8.5% for the open procedure. A total of 9 patients required conversion to the open procedure for perforation, bleeding, or dissection difficulties. However, in the last 350 cases no conversions have been necessary. Most patients are now being discharged from hospital on the day after surgery with some patients being discharged on the same day as surgery. The overall reoperation rate, both for early postoperative morbidity and for late poor outcome, was 3.9% wit...Continue Reading

References

Mar 19, 1992·The New England Journal of Medicine·J E Richter
Jan 1, 1989·Digestion·E C Klinkenberg-Knol, S G Meuwissen
Oct 1, 1987·Archives of Internal Medicine·D A Lieberman
Jan 1, 1986·Journal of Clinical Gastroenterology·L F Johnson, T R DeMeester
Jun 1, 1985·Archives of Surgery·P E DonahueC T Bombeck
Mar 1, 1995·Archives of Surgery·D W Rattner, D C Brooks
May 1, 1994·American Journal of Surgery·L Swanstrom, R Wayne
Oct 1, 1993·Surgical Laparoscopy & Endoscopy·J M WeertsP E Ferron
Aug 1, 1993·Journal of Laparoendoscopic Surgery·M J O'Reilly, S G Mullins
Jan 1, 1994·American Journal of Surgery·H B BittnerT N Pappas
Jul 1, 1993·American Journal of Surgery·J D Urschel

❮ Previous
Next ❯

Citations

Jun 24, 2006·Annals of Surgery·Atif IqbalCharles J Filipi
Jan 18, 2007·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·M Y A LindeboomA A M Masclee
Jan 8, 2008·Alimentary Pharmacology & Therapeutics·M P Schwartz, A J P M Smout
Jun 12, 2003·Gastrointestinal Endoscopy Clinics of North America·Nimish Vakil, Christino Canga
Jan 25, 2003·The American Journal of Medicine·Nimish VakilRussell Kirby
Mar 29, 2003·ANZ Journal of Surgery·Reginald V N Lord
Mar 29, 2000·Alimentary Pharmacology & Therapeutics·N D Yeomans, J Dent
Dec 16, 2006·Digestive Diseases and Sciences·Kyung W NohRonald A Hinder
Feb 19, 2002·Gastroenterology Nursing : the Official Journal of the Society of Gastroenterology Nurses and Associates·B S AronsonC Quaggin
Jan 16, 2003·The American Journal of Gastroenterology·Maud A LindeboomAd A M Masclee
May 25, 2002·The British Journal of Surgery·J R BessellD C Gotley
Jan 22, 2010·The Cochrane Database of Systematic Reviews·Jonathan Re ReesRebecca C Fitzgerald
Jul 11, 2001·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·A L BowerF J Brody
Nov 18, 2003·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·Herbert C WolfsenKenneth R DeVault
Aug 10, 2005·The American Journal of Gastroenterology·Diego M DiazBenjamin D Gold
Apr 14, 2000·The American Journal of Gastroenterology·P J KlinglerK R DeVault
Mar 23, 2012·Innovations : Technology and Techniques in Cardiothoracic and Vascular Surgery·Giulia VeronesiLorenzo Spaggiari
Jan 31, 2002·World Journal of Gastroenterology : WJG·Edwin J Zarling

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.