The survival strategies of malaria parasite in the red blood cell and host cell polymorphisms.

Malaria Research and Treatment
Gunanidhi DhangadamajhiManoranjan Ranjit

Abstract

Parasite growth within the erythrocyte causes dramatic alterations of host cell which on one hand facilitates nutrients acquisition from extracellular environment and on other hand contributes to the symptoms of severe malaria. The current paper focuses on interactions between the Plasmodium parasite and its metabolically highly reduced host cell, the natural selection of numerous polymorphisms in the genes encoding hemoglobin and other erythrocyte proteins.

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Feb 15, 2014·Parasitology Research·Murtala Bindawa Isah, Mohammed Auwal Ibrahim
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Jul 24, 2012·Transactions of the Royal Society of Tropical Medicine and Hygiene·Ronnaly RoutManoranjan Ranjit
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May 26, 2017·Biomedicines·Nik Abdul Aziz Nik KamarudinKhairul Mohd Fadzli Mustaffa

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Methods Mentioned

BETA
gene knockout
acetylation

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