The symptom phenotype of oncology outpatients remains relatively stable from prior to through 1 week following chemotherapy

European Journal of Cancer Care
Christine MiaskowskiN Kearney

Abstract

Some oncology outpatients experience a higher number of and more severe symptoms during chemotherapy (CTX). However, little is known about whether this high risk phenotype persists over time. Latent transition analysis (LTA) was used to examine the probability that patients remained in the same symptom class when assessed prior to the administration of and following their next dose of CTX. For the patients whose class membership remained consistent, differences in demographic and clinical characteristics, and quality of life (QOL) were evaluated. The Memorial Symptom Assessment Scale (MSAS) was used to evaluate symptom burden. LTA was used to identify subgroups of patients with distinct symptom experiences based on the occurrence of the MSAS symptoms. Of the 906 patients evaluated, 83.9% were classified in the same symptom occurrence class at both assessments. Of these 760 patients, 25.0% were classified as Low-Low, 44.1% as Moderate-Moderate and 30.9% as High-High. Compared to the Low-Low class, the other two classes were younger, more likely to be women and to report child care responsibilities, and had a lower functional status and a higher comorbidity scores. The two higher classes reported lower QOL scores. The use of LTA ...Continue Reading

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Citations

Oct 26, 2016·Seminars in Oncology Nursing·Christine Miaskowski
Jan 1, 2019·PloS One·Nikolaos PapachristouChristine Miaskowski
Jan 21, 2020·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Fay WrightChristine Miaskowski
Aug 29, 2020·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Emmika ElkinChristine Miaskowski
Dec 9, 2017·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Pierre MichelPascal Auquier
Feb 21, 2019·Scientific Reports·Nikolaos PapachristouChristine Miaskowski
Sep 2, 2017·Journal of Pain and Symptom Management·Nikoloas PapachristouChristine Miaskowski
Jan 18, 2021·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Yufen LinChristine Miaskowski
Feb 16, 2019·Journal of Pain and Symptom Management·Jacquelyn RussellChristine Miaskowski
Jul 13, 2021·Fatigue : Biomedicine, Health & Behavior·Kord M KoberChristine Miaskowski
Jul 5, 2021·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Lisa MorseChristine Miaskowski
Nov 18, 2021·Journal of Cancer Survivorship : Research and Practice·Arnold L PotoskyBryce B Reeve

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