The synergistic effect of self-assembly and visible-light induced the oxidative C-H acylation of N-heterocyclic aromatic compounds with aldehydes

Chemical Communications : Chem Comm
Lingling ZhangAiwen Lei

Abstract

Constructing carbon-carbon bonds through oxidative cross-coupling between two hydrocarbon compounds is regarded as a foundational issue in green chemistry. High atom-economy and mild conditions are long term pursued goals in this field. Herein, we developed a visible-light mediated direct cross-coupling between N-heterocycles and aldehydes without the requirement of a photocatalyst. Several N-heterocycles afforded the acylation products with aromatic or aliphatic aldehydes in good yields. The reaction can be conducted under room temperature and easily scaled up.

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Citations

May 29, 2019·Chemical Communications : Chem Comm·Jeremy M LearDavid A Nagib
Aug 3, 2019·Organic & Biomolecular Chemistry·Yan XiaoJiang Cheng
Sep 13, 2019·Chemistry, an Asian Journal·Shiv ChandKrishna Nand Singh
Jul 30, 2019·ChemSusChem·Ioanna K SideriChristoforos G Kokotos
Oct 31, 2020·Organic & Biomolecular Chemistry·Sonam JaspalAnil Kumar
Mar 13, 2019·Organic Letters·Xing-An LiangAiwen Lei
May 28, 2019·Journal of the American Chemical Society·Inwon KimSungwoo Hong
Jan 18, 2022·Chemical Communications : Chem Comm·Vishal Jyoti RoySudipta Raha Roy

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Methods Mentioned

BETA
acylation
NMR

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