PMID: 5914691Feb 1, 1966

The synthesis of DNA, RNA, and nuclear protein in normal and tumor strain cells. II. Fresh embryo mouse cells

The Journal of Cell Biology
J Seed

Abstract

Interferometric and photometric measurements have been made on replicating embryo mouse cell cultures. From a study of the relations between successive physical measurements on individual cells, it was found that the net syntheses of DNA, nuclear RNA, nuclear protein, and cytoplasmic RNA are closely associated during interphase. In auxiliary experiments, an inhibition of the onset of DNA synthesis (produced by a dose of X-rays) was found to block the majority of the accumulation of nuclear protein and nuclear RNA. These results are consistent with others previously reported in dividing cell cultures freshly prepared from normal tissues.

Citations

Jan 1, 1968·Zeitschrift für Krebsforschung·S ComorosanD Sandru
Apr 1, 1979·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·U K Ehmann, K T Wheeler
Apr 1, 1971·European Journal of Biochemistry·P R Harrison

Related Concepts

Cell Division Phases
Cell Nucleus
DNA, Double-Stranded
Embryonic Structures, Mammalian
Karyometric Image Analysis
Photometry
Effects of Radiation
RNA
Protein Biosynthesis

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