The synthesis of enantiomerically pure [2.2]paracyclophane derivatives

Organic & Biomolecular Chemistry
Gareth J Rowlands

Abstract

[2.2]Paracyclophane is a fascinating molecule that offers great potential in a wide range of chemical disciplines. Currently, the synthesis of the majority of enantiomerically pure [2.2]paracyclophane derivatives is based on the resolution of a small number of starting materials or individual resolution procedures are developed for each new compound. The development of more general routes to these valuable compounds via the resolution of a common intermediate is discussed. Ultimately, it would be preferable to synthesise these valuable compounds without recourse to resolution and ideas for this rewarding goal are postulated.

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Citations

Jan 1, 2010·Acta Crystallographica. Section E, Structure Reports Online·Guojun Jin, Yinghui Lu
May 30, 2009·Beilstein Journal of Organic Chemistry·Gareth J Rowlands, Richard J Seacome
Feb 18, 2014·Journal of the American Chemical Society·Yasuhiro MorisakiYoshiki Chujo
Nov 3, 2016·Organic & Biomolecular Chemistry·Krishanthi P JayasunderaGareth J Rowlands
Jan 10, 2019·Chemistry, an Asian Journal·Katsuaki KikuchiYasuhiro Morisaki
Apr 7, 2010·Dalton Transactions : an International Journal of Inorganic Chemistry·Richard J SeacomeGareth J Rowlands
Sep 25, 2010·Chemical Communications : Chem Comm·J Robin FultonGareth J Rowlands
Dec 20, 2011·Chemical Communications : Chem Comm·Nathalie DendeleChristopher J Richards
Jun 5, 2013·Chemical Communications : Chem Comm·Jérémy StemperAngela Marinetti
Jun 4, 2014·Chemistry : a European Journal·Yasuhiro MorisakiYoshiki Chujo
Aug 18, 2017·Chemistry : a European Journal·Carolin BraunStefan Bräse
Jul 30, 2016·Chemistry, an Asian Journal·Yasuhiro MorisakiYoshiki Chujo
Aug 9, 2020·Chemistry : a European Journal·Genki NambaYasuhiro Morisaki
Apr 24, 2021·Beilstein Journal of Organic Chemistry·David Weinzierl, Mario Waser
Dec 16, 2020·The Journal of Organic Chemistry·Damien DeschampsStéphane Perrio
Dec 1, 2021·Chemistry, an Asian Journal·Kentaro TanakaYasuhiro Morisaki

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