The synthetic cationic lipid diC14 activates a sector of the Arabidopsis defence network requiring endogenous signalling components

Molecular Plant Pathology
Damián Alejandro CambiagnoMaría Elena Alvarez

Abstract

Natural and synthetic elicitors have contributed significantly to the study of plant immunity. Pathogen-derived proteins and carbohydrates that bind to immune receptors, allow the fine dissection of certain defence pathways. Lipids of a different nature that act as defence elicitors, have also been studied, but their specific effects have been less well characterized, and their receptors have not been identified. In animal cells, nanoliposomes of the synthetic cationic lipid 3-tetradecylamino-tert-butyl-N-tetradecylpropionamidine (diC14) activate the TLR4-dependent immune cascade. Here, we have investigated whether this lipid induces Arabidopsis defence responses. At the local level, diC14 activated early and late defence gene markers (FRK1, WRKY29, ICS1 and PR1), acting in a dose-dependent manner. This lipid induced the salicylic acid (SA)-dependent, but not jasmonic acid (JA)-dependent, pathway and protected plants against Pseudomonas syringae pv. tomato (Pst), but not Botrytis cinerea. diC14 was not toxic to plant or pathogen, and potentiated pathogen-induced callose deposition. At the systemic level, diC14 induced PR1 expression and conferred resistance against Pst. diC14-induced defence responses required the signalling pr...Continue Reading

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Citations

Jun 9, 2016·Molecular Plant-microbe Interactions : MPMI·Georgina FabroMaría Elena Alvarez
Jul 30, 2019·Molecular Plant Pathology·Romain SchellenbergerStéphan Dorey
Sep 27, 2018·Planta·Carolina GrandellisJorgelina Ottado
Jul 12, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Mathilde RobineauEssaid Ait Barka
Jun 6, 2018·Scientific Reports·W Patricio Luzuriaga-LoaizaStephan Dorey
Jul 28, 2017·Langmuir : the ACS Journal of Surfaces and Colloids·Mehmet Nail NasirMagali Deleu

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