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The TB-specific CD4(+) T cell immune repertoire in both cynomolgus and rhesus macaques largely overlap with humans

Tuberculosis

Dec 1, 2015

Bianca R MotheAlessandro Sette

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Abstract

Non-human primate (NHP) models of tuberculosis (TB) immunity and pathogenesis, especially rhesus and cynomolgus macaques, are particularly attractive because of the high similarity of the human and macaque immune systems. However, little is known about the MHC class II epitopes recogniz...read more

Mentioned in this Paper

Cell Secretion
Antigens, Immunodominant
Immune System
Latent Infection
Species
Immunization Domain
Activation of T Cell Mediated Immune Response to Tumor Cell
QUANTIFERON-TB GOLD
Macaca
Homologous Gene
1
32
Paper Details
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The TB-specific CD4(+) T cell immune repertoire in both cynomolgus and rhesus macaques largely overlap with humans

Tuberculosis

Dec 1, 2015

Bianca R MotheAlessandro Sette

PMID: 26526557

DOI: 10.1016/j.tube.2015.07.005

Abstract

Non-human primate (NHP) models of tuberculosis (TB) immunity and pathogenesis, especially rhesus and cynomolgus macaques, are particularly attractive because of the high similarity of the human and macaque immune systems. However, little is known about the MHC class II epitopes recogniz...read more

Mentioned in this Paper

Cell Secretion
Antigens, Immunodominant
Immune System
Latent Infection
Species
1
32

Related Papers

Paper Details
References
  • References111
  • Citations11
12345...
  • References111
  • Citations11
12

Get paper from

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