The therapeutic relationship and adherence to antipsychotic medication in schizophrenia.

PloS One
Rosemarie McCabeStefan Priebe

Abstract

Previous research has shown that a better therapeutic relationship (TR) predicts more positive attitudes towards antipsychotic medication, but did not address whether it is also linked with actual adherence. This study investigated whether the TR is associated with adherence to antipsychotics in patients with schizophrenia. 134 clinicians and 507 of their patients with schizophrenia or a related psychotic disorder participated in a European multi-centre study. A logistic regression model examined how the TR as rated by patients and by clinicians is associated with medication adherence, adjusting for clinician clustering and symptom severity. Patient and clinician ratings of the TR were weakly inter-correlated (r(s) = 0.13, p = 0.004), but each was independently linked with better adherence. After adjusting for patient rated TR and symptom severity, each unit increase in clinician rated TR was associated with an increase of the odds ratio of good compliance by 65.9% (95% CI: 34.6% to 104.5%). After adjusting for clinician rated TR and symptom severity, for each unit increase in patient rated TR the odds ratio of good compliance was increased by 20.8% (95% CI: 4.4% to 39.8%). A better TR is associated with better adherence to med...Continue Reading

References

Jun 1, 1988·Journal of Consulting and Clinical Psychology·B E Wolfe, M R Goldfried
Aug 1, 1987·Hospital & Community Psychiatry·J F ClarkinJ L Crilly
Jan 1, 1987·Schizophrenia Bulletin·S R KayL A Opler
Jul 1, 1995·Psychiatric Services : a Journal of the American Psychiatric Association·M S Neale, R A Rosenheck
Sep 1, 1993·The Journal of Nervous and Mental Disease·S Priebe, T Gruyters
May 1, 1997·The Journal of Clinical Psychiatry·M WeissV Zicherman
Dec 2, 1998·Community Mental Health Journal·W D KlinkenbergG A Morse
Apr 1, 1995·Journal of Mental Health Administration·P SolomonM A Delaney
Jul 7, 2000·Journal of Consulting and Clinical Psychology·D J MartinM K Davis
Aug 22, 2001·European Psychiatry : the Journal of the Association of European Psychiatrists·G DonohoeE O'Callaghan
May 16, 2002·The Journal of Nervous and Mental Disease·Alexander N Ortega, Robert Rosenheck
Apr 30, 2003·Psychiatric Services : a Journal of the American Psychiatric Association·Dawn I VelliganAlexander L Miller
Aug 21, 2003·European Psychiatry : the Journal of the Association of European Psychiatrists·R McCabe, S Priebe
Jan 2, 2004·The British Journal of Psychiatry : the Journal of Mental Science·Jim Van OsPhilippe Robert
Nov 22, 2005·Care Management Journals : Journal of Case Management ; the Journal of Long Term Home Health Care·Robert J CalsynMatthew R Lemming
May 19, 2006·Schizophrenia Bulletin·Dawn I VelliganAlexander L Miller
Aug 3, 2006·Journal of Consulting and Clinical Psychology·Brandon A Gaudiano, Ivan W Miller
Nov 6, 2007·The British Journal of Psychiatry : the Journal of Mental Science·Stefan PriebeDonna J Wright
Dec 7, 2007·The British Journal of Psychiatry : the Journal of Mental Science·Ulrich M JunghanMike Slade

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Citations

Apr 30, 2014·Schizophrenia Bulletin·W Wolfgang FleischhackerPeter Woodruff
Jan 24, 2014·Community Mental Health Journal·Iglika VassilevaTuran Asan
Jul 23, 2013·Current Opinion in Psychiatry·Gricelda Gómez, Emilio Aillach
Oct 8, 2013·World Psychiatry : Official Journal of the World Psychiatric Association (WPA)·Rose McCabe
Dec 12, 2012·Respiratory Medicine·Ilaria BaiardiniGiorgio Walter Canonica
Apr 30, 2016·Journal of Child and Adolescent Psychopharmacology·Alessandro S De NadaiEric A Storch
Apr 25, 2015·PloS One·Friederike X E HöferStefanie K Gairing
Jul 23, 2016·The British Journal of Psychiatry : the Journal of Mental Science·Rose McCabeStefan Priebe
Apr 4, 2017·Health Expectations : an International Journal of Public Participation in Health Care and Health Policy·Helen LloydMichele Peters
Jan 13, 2017·World Journal of Psychiatry·Subho Chakrabarti
May 12, 2018·Topics in Cognitive Science·Rose McCabe, Patrick G T Healey
Jan 20, 2017·Epidemiology and Psychiatric Sciences·W Rössler, R E Drake
Mar 25, 2019·Clinical Psychopharmacology and Neuroscience : the Official Scientific Journal of the Korean College of Neuropsychopharmacology·Jhin Goo ChangChan-Hyung Kim
Aug 14, 2020·International Journal of Psychiatry in Clinical Practice·Rocío Torrecilla-OlavarrietaFrancisco González-Saiz
Jun 11, 2014·Journal of Behavioral Medicine·Heather F de Vries McClintockHillary R Bogner
Feb 9, 2017·Journal of the American Psychiatric Nurses Association·Karen Goyette Pounds
Jul 25, 2017·BMC Psychiatry·Joanne LloydMichele Peters
Nov 28, 2018·The Psychiatric Quarterly·Lucie KondrátováPetr Winkler
Apr 30, 2019·Frontiers in Psychiatry·Henning HachtelChristian G Huber
Sep 27, 2019·The American Journal of Bioethics : AJOB·Adam BoreckyAlex Dubov
Dec 3, 2016·Administration and Policy in Mental Health·Johanne EliacinAngela L Rollins
Oct 27, 2016·Social Psychiatry and Psychiatric Epidemiology·Stephen Robert PuntisTom Burns
Oct 11, 2017·Journal of Psychosocial Nursing and Mental Health Services·Elizabeth CortRobert Howard
Mar 30, 2020·The Journal of Nervous and Mental Disease·Héloïse da CostaNicolas Franck
Apr 14, 2019·International Journal of Environmental Research and Public Health·Winnie W KungDebbie Huang
Jun 25, 2020·International Journal of Mental Health Systems·Wendy ShoesmithSue Fyfe
Dec 10, 2020·Psychiatry Research·Marian SurmannRebekka Lencer
Aug 20, 2021·Journal of Clinical Psychopharmacology·Madeline LimJimmy Lee

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SPSS
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