"The Therapy of Elimination First" for Early Acute Mastitis: A Systematic Review and Meta-Analysis

Evidence-based Complementary and Alternative Medicine : ECAM
Ying ZhangMin Zhou

Abstract

We evaluated the effectiveness of "the therapy of elimination first" in early acute mastitis, using four databases (CNKI, Wanfang, Embase, and PubMed). The study incorporated 2508 patients from 16 randomized controlled trials (RCTs). Included trials used Chinese oral medicine and applied the principle of "Eliminating Therapy" for the early treatment of acute mastitis, with simple antibiotic treatment as a control group. Meta-analysis showed significant differences between the overall effectiveness of oral Chinese medicine using Eliminating Therapy (OCM-ET) and western medicine using antibiotics (WM-A) (odds ratio [OR] = 4.43, 95% confidence interval [CI] = 3.21-6.12, Z = 9.04, and P < 0.00001). Analysis of subgroups based on the use of classic or self-made preparations of the medicines showed smaller statistical heterogeneity among the different subgroups (P > 0.05, I2 ≤ 50%). The OCM-ET group showed significantly shorter pain relief times [mean difference (MD) = -3.08, 95% CI = (-5.90, -0.26), and P = 0.03] and cure times [MD = -6.27, 95% CI = (-9.68, -2.85), and P = 0.0003] than did the WM-A group. Our findings suggest that OCM-ET can shorten the duration of pain and improve cure time in early acute mastitis patients, with fe...Continue Reading

References

Feb 1, 1989·The Journal of Hospital Infection·L FrostE Seiersen
Jul 1, 1984·American Journal of Obstetrics and Gynecology·A C ThomsenS Maigaard
Sep 19, 2002·Veterinary Ophthalmology·K C Barnett, J C M Lewis
Oct 2, 2007·Journal of Cardiovascular Medicine·Salvatore AzzarelliAntonio Fiscella
May 16, 2009·Journal of Nanoscience and Nanotechnology·Shanghua LiMamoun Muhammed
Apr 1, 2011·Journal of Nanoscience and Nanotechnology·P D MarcatoN Durán
Oct 20, 2011·BMJ : British Medical Journal·Julian P T HigginsUNKNOWN Cochrane Statistical Methods Group
Jun 12, 2012·Journal of Crohn's & Colitis·B MeijerA S Day
Jun 19, 2014·Experimental and Therapeutic Medicine·Jia-Mei YaoLin-Lin Zhao
Aug 30, 2014·Forensic Science, Medicine, and Pathology·Vladimir Zivković, Slobodan Nikolić
Dec 3, 2016·Regenerative Medicine·Erin A Kimbrel, Robert Lanza

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