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The three 'C' s of chromosome conformation capture: controls, controls, controls

Nature Methods

Dec 22, 2005

Job Dekker

Abstract

Transcription regulation in higher eukaryotes is controlled by regulatory elements such as enhancers that are recognized by transcription factors. In many cases regulatory elements can be located at distances up to several megabases from their target genes. Recent evidence shows that lo...read more

Mentioned in this Paper

Transcriptional Regulation
Gene Expression
Genomics
Regulatory Elements, Transcriptional
Chromosomes
DNA Conformation
Cistron
Transcription Factor
Reproducibility of Results
Nested Polymerase Chain Reaction
536
Paper Details
References
  • References15
  • Citations174
12
  • References15
  • Citations174
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Cis- & Trans-Regulatory Elements

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The three 'C' s of chromosome conformation capture: controls, controls, controls

Nature Methods

Dec 22, 2005

Job Dekker

PMID: 16369547

DOI: 10.1038/nmeth823

Abstract

Transcription regulation in higher eukaryotes is controlled by regulatory elements such as enhancers that are recognized by transcription factors. In many cases regulatory elements can be located at distances up to several megabases from their target genes. Recent evidence shows that lo...read more

Mentioned in this Paper

Transcriptional Regulation
Gene Expression
Genomics
Regulatory Elements, Transcriptional
Chromosomes
DNA Conformation
Cistron
Transcription Factor
Reproducibility of Results
Nested Polymerase Chain Reaction
536

Similar Papers Found In These Feeds

Cis & Trans Regulatory Elements

Cis-regulatory elements are regions DNA that regulate the transcription of neighbouring genes. Trans-regulatory elements are genomic loci that regulate the expression of distant genes. Here is the latest research on CREs and TREs.

Cis- & Trans-Regulatory Elements

Cis-regulatory elements are DNA regions that regulate the transcription of neighbouring genes. Trans-regulatory elements are genomic loci that regulate the expression of distant genes by encoding transcription factors. Here is the latest research on CREs and TREs.

Related Papers

Paper Details
References
  • References15
  • Citations174
12
  • References15
  • Citations174
12345...
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