The topically irritant substance: essentials - bio-tests - predictions

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K BucherD Walz

Abstract

The paper describes a method for judging the irritative potentialities of substances; proposes a scoring system with which the 'ordinary' risks of many of the abundant marketed products for washing, cleaning etc. may be predicted without biological testing; discusses pharmacodynamic and pharmacokinetic aspects of topical irritancy and points to the problems of extrapolating from animal experiments to man.

References

Jan 1, 1977·Toxicology and Applied Pharmacology·P ConquetB Plazonnet
Dec 1, 1972·Food and Cosmetics Toxicology·L G ScharpfR E Kelly
Jan 1, 1971·American Journal of Optometry and Archives of American Academy of Optometry·F N Marzulli, M E Simon

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Citations

Feb 1, 1985·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·E Bosshard
Feb 1, 1985·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·D W Swanston
Feb 1, 1985·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·C Gloxhuber, W Kästner
Feb 1, 1985·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·D Walz
Nov 1, 1990·Contact Dermatitis·J J HostynekH I Maibach
Mar 15, 2002·Nature·Eve Marder
Jul 15, 2021·International Journal of Toxicology·Wilbur JohnsonBart Heldreth

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