The toxicological mechanisms and detoxification of depleted uranium exposure

Environmental Health and Preventive Medicine
Yong-Chao YueWei He

Abstract

Depleted uranium (DU) has been widely applied in industrial and military activities, and is often obtained from producing fuel for nuclear reactors. DU may be released into the environment, polluting air, soil, and water, and is considered to exert both radiological and chemical toxicity. In humans and animals, DU can induce multiple health effects, such as renal tubular necrosis and bone malignancies. This review summarizes the known information on DU's routes of entry, mechanisms of toxicity, and health effects. In addition, we survey the chelating agents used in ameliorating DU toxicity.

References

Mar 1, 1991·The Science of the Total Environment·J D Harrison
May 1, 1991·Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology·J M LlobetJ L Domingo
Jan 1, 1982·Virchows Archiv. B, Cell Pathology Including Molecular Pathology·F N GhadiallyS Yang-Steppuhn
Apr 1, 1983·Environmental Research·B M de ReyR L Cabrini
Jul 6, 2000·Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine·C DinseC Bouvier
Sep 3, 2002·Toxicology·John F KalinichDavid E McClain
Dec 26, 2002·Journal of Environmental Radioactivity·A BleiseW Burkart
Jun 14, 2003·TheScientificWorldJournal·Scott J Markich
Oct 7, 2003·Radiation Protection Dosimetry·V LemercierJ M Scherrmann
Apr 27, 2004·Revue D'épidémiologie Et De Santé Publique·M TirmarcheM Telle-Lamberton
Jan 1, 2005·The Science of the Total Environment·L A Di LellaF Riccobono
May 21, 2005·Toxicology Letters·Victoria LinaresJosé L Domingo
Feb 3, 2006·Environmental Health Perspectives·Claire B Ernhart
Feb 3, 2006·The Journal of Clinical Investigation·Giuseppe RemuzziAndrea Remuzzi
Feb 28, 2006·Archives of Toxicology·E TissandieM Souidi
Jul 15, 2006·Environmental Toxicology·Jalal PourahmadRuhollah Ghalandari
Sep 26, 2006·Biochimie·Eric AnsoborloValérie Moulin
Nov 25, 2006·Archives of Toxicology·Adaikkappan PeriyakaruppanGovindarajan T Ramesh
Dec 14, 2006·Health Physics·Satoshi FukudaYuyuan Xie
Jun 15, 2007·Toxicological Sciences : an Official Journal of the Society of Toxicology·Isabelle DublineauPatrick Gourmelon
Nov 14, 2007·Toxicological Sciences : an Official Journal of the Society of Toxicology·Dany S MullerMarie-Hélène Hengé-Napoli
Mar 28, 2009·Biochimie·Alexandra C MillerRafael Rivas
Jun 9, 2009·Toxicology Letters·Benjamin B TournierFabrice Petitot
Sep 23, 2009·Antioxidants & Redox Signaling·John W CalvertDavid J Lefer
Sep 26, 2009·Journal of Pharmaceutical Sciences·Aurélie SpagnulElias Fattal
Dec 17, 2009·Chemical Research in Toxicology·Hong XieJohn Pierce Wise
Feb 9, 2010·Journal of Medicinal Food·Kürşad YaparEmine Yalçin
Mar 2, 2010·Amino Acids·Hideo Kimura
Apr 30, 2010·The Journal of Pharmacology and Experimental Therapeutics·Jerzy Bełtowski
Jun 18, 2010·Toxicological Sciences : an Official Journal of the Society of Toxicology·Laura Vicente-VicenteAna Isabel Morales
Mar 31, 2012·Chemical Research in Toxicology·Claude VidaudDaniel Meyer

❮ Previous
Next ❯

Citations

Oct 18, 2019·Biological Trace Element Research·Shuang WangYuhui Hao
Jun 27, 2019·Renal Failure·Nadezda PetejovaVladimir Teplan
Dec 19, 2020·International Journal of Molecular Sciences·Jacek BajHanna Karakula-Juchnowicz
Jan 6, 2021·Environmental Pollution·Libing YuZhonghua Xiong
Jun 26, 2020·Neurotoxicology·Michelle R Joyce, Kathleen F Holton
Mar 10, 2020·Inorganic Chemistry·Jerome KretzschmarThorsten Stumpf

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Radiological Protection : Official Journal of the Society for Radiological Protection
R Wakeford
© 2022 Meta ULC. All rights reserved