The transversus abdominis plane block, when used as part of a multimodal regimen inclusive of intrathecal morphine, does not improve analgesia after cesarean delivery

Regional Anesthesia and Pain Medicine
Joseph CostelloJose C A Carvalho

Abstract

The transversus abdominis plane (TAP) block has been shown to provide analgesia for lower abdominal wall incisions. We evaluated the efficacy of the TAP block for post-cesarean delivery (CD) patients used as a part of a multimodal regimen. Women undergoing elective CD under spinal anesthesia were randomized to receive the TAP block with ropivacaine (n = 50) or placebo (n = 50), in addition to a standard postoperative analgesic regimen inclusive of intrathecal opioids. At the end of the surgical procedure, all the patients received bilateral TAP blocks under real-time ultrasound guidance, with either 20 mL of ropivacaine 0.375% or saline, on each side. Each patient was assessed at 6, 12, 24, and 48 hrs postoperatively, and again 6 weeks after the surgical procedure. The primary outcome was the difference in visual analog scale pain scores with movement at 24 hrs postpartum. Other outcomes assessed were analgesic consumption, maternal satisfaction, and incidence of adverse effects. One hundred women were recruited, and 96 completed the study. The mean (SD) visual analog scale pain scores on movement at 24 hrs were not different between the ropivacaine and placebo groups (3.4 [2.4] and 3.2 [2.2] cm, respectively, P = 0.47). The pa...Continue Reading

Associated Clinical Trials

References

Mar 1, 1997·British Journal of Anaesthesia·D J RosarioA T Raftery
Aug 1, 1997·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·O P RosaegB Krepski
Aug 24, 2002·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Elizabeth A BellUNKNOWN Duke Women's Anesthesia Research Group
Dec 17, 2003·Acta Anaesthesiologica Scandinavica·L NikolajsenH Kehlet
Sep 30, 2005·Anesthesia and Analgesia·Brendan CarvalhoAlex Macario
Oct 27, 2007·Regional Anesthesia and Pain Medicine·John G McDonnellJohn G Laffey
Oct 22, 2008·Anesthesia and Analgesia·Zorica JankovicFrances Archer

❮ Previous
Next ❯

Citations

Nov 28, 2012·Journal of Anesthesia·Guilherme Holck, William Camann
May 25, 2012·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Basem M MishrikyAshraf S Habib
Dec 25, 2012·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Farheen Mirza, Brendan Carvalho
Dec 14, 2011·International Journal of Obstetric Anesthesia·L BollagR Landau
Mar 13, 2013·International Journal of Obstetric Anesthesia·R LandauC Ortner
Jan 6, 2012·British Medical Bulletin·Mark Rollins, Jennifer Lucero
May 13, 2010·Regional Anesthesia and Pain Medicine·Peter D Hebbard, Colin F Royse
Jul 1, 2010·Regional Anesthesia and Pain Medicine·Danielle Factor, Ki Jinn Chin
Jan 31, 2012·Regional Anesthesia and Pain Medicine·Faraj W AbdallahRichard Brull
Feb 9, 2012·Anesthesiology Research and Practice·Mark J YoungSadeq A Quraishi
Sep 8, 2011·Journal of Anaesthesiology, Clinical Pharmacology·Rao V Kadam, J B Field
Feb 2, 2011·Annales Françaises D'anesthèsie Et De Rèanimation·H Beloeil, P J Zetlaoui
Apr 26, 2014·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Dolores M McKeenAaron Pink
Aug 27, 2014·Seminars in Perinatology·Allison Lee
Aug 27, 2013·Clinics in Perinatology·Anne Lavoie, Paloma Toledo
Mar 7, 2012·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Linda Le-WendlingAndré P Boezaart
Jun 1, 2013·Annales Françaises D'anesthèsie Et De Rèanimation·P DerasP Colson
Dec 12, 2012·Revista española de anestesiología y reanimación·L CánovasL Pérez
Sep 15, 2012·The Surgeon : Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland·J M FindlayP Congahan
Feb 9, 2012·Anaesthesia and Intensive Care·Gavin Pattullo
Mar 13, 2012·International Journal of Obstetric Anesthesia·N J McDonnell, M J Paech
Feb 12, 2011·International Journal of Obstetric Anesthesia·J M Mhyre
Nov 30, 2010·International Journal of Obstetric Anesthesia·R J Kearns, S J Young
Sep 13, 2012·Pain Practice : the Official Journal of World Institute of Pain·Robert TaylorChristian C Apfel
Nov 15, 2011·Paediatric Anaesthesia·Harald Willschke, Stephan Kettner
Feb 24, 2010·Acta Anaesthesiologica Scandinavica·P L PetersenJ B Dahl
May 4, 2016·Indian Journal of Anaesthesia·Maitreyi Gajanan MankikarPoonam Sachin Ghodki
Jun 6, 2012·Anesthesiology Research and Practice·Nils BjerregaardBodil Steen Rasmussen
Jul 1, 2015·Brazilian Journal of Anesthesiology·Javier RipollésJosé Calvo
Jul 7, 2015·Revista brasileira de anestesiologia·Javier RipollésJosé Calvo

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.