PMID: 11949962Apr 13, 2002

The treatment of endometriosis: a review of the evidence

Annals of the New York Academy of Sciences
D L Olive, Elizabeth A Pritts


The treatment of endometriosis focuses upon amelioration of two symptoms: pain and infertility. The treatment of endometriosis-associated pain has been well studied and all major medical therapies appear to be superior to placebo. In addition, none seems to be drastically better than another. Surgical therapy also appears to be efficacious, albeit with a relatively high rate of recurrence of symptoms following conservative surgical intervention. There are no trials comparing the relative value of medical versus surgical therapy. Combination surgery/medical therapy has several high-quality trials for evaluation, but its value remains unclear. The treatment of endometriosis-associated infertility presents a different picture: medical therapy has not been shown to be of any value and may prove detrimental to fertility. Surgical treatment does improve fertility, probably for all stages of disease. Assisted reproduction also seems to be efficacious, with both controlled ovarian hyperstimulation and intrauterine insemination as well as in vitro fertilization shown to be of benefit. Finally, the combination of in vitro fertilization and either medical or surgical therapy may be beneficial with advanced endometriosis, but further study...Continue Reading


Oct 29, 2004·Current Pain and Headache Reports·J Jarrell
May 5, 2004·Best Practice & Research. Clinical Obstetrics & Gynaecology·Erling EkerhovdSeth Granberg
Jan 8, 2013·Best Practice & Research. Clinical Obstetrics & Gynaecology·Stephan Gordts
Aug 7, 2013·Nutrition Research Reviews·Charlotte van RooijenWouter H Hendriks
May 2, 2006·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Ellen Silver HighfieldPeter M Wayne
Jan 22, 2005·Annual Review of Medicine·D H Barlow, S H Kennedy
Nov 1, 2005·Women's Health·Carla Burks-WicksFritz Wieser
Dec 17, 2008·Women's Health·Xishi Liu, Sun-Wei Guo
Oct 12, 2010·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·A BadawyL Sherif
May 2, 2006·Fertility and Sterility·Erkut Attar, Serdar E Bulun
Mar 11, 2006·Journal of Minimally Invasive Gynecology·Temel CeyhanIskender Baser
Jul 13, 2005·Fertility and Sterility·Yu-Chi WangShu-Huei Kao
Apr 20, 2016·Archives of Gynecology and Obstetrics·Wei LiuCui-Xia Guo
Apr 17, 2010·Reproductive Biomedicine Online·Gernot HudelistChristian F Singer
Oct 17, 2003·Endocrinology and Metabolism Clinics of North America·Elizabeth A Pritts, Robert N Taylor
Nov 16, 2004·Lancet·Linda C Giudice, Lee C Kao
Apr 5, 2017·Reproductive Sciences·Elliott G RichardsGaurang S Daftary
Oct 8, 2004·Expert Opinion on Therapeutic Targets·Warren B Nothnick
May 8, 2010·Internal and Emergency Medicine·Massimo MontaltoGiovanni Gasbarrini
Jul 8, 2016·Endocrinology·Luiz F CorreaGaurang S Daftary
Aug 31, 2014·Pain·Samah HassanGillian Einstein


Jul 1, 1992·American Journal of Obstetrics and Gynecology·G B CandianiG Di Nola
Jul 1, 1992·American Journal of Obstetrics and Gynecology·M InoueA Fujii
Nov 1, 1992·American Journal of Obstetrics and Gynecology·J M WheelerJ D Miller
May 1, 1991·The Australian & New Zealand Journal of Obstetrics & Gynaecology·I S FraserP D Sutherland
Feb 1, 1990·American Journal of Obstetrics and Gynecology·R Rolland, P F van der Heijden
Jun 1, 1990·Fertility and Sterility·S H KennedyR W Shaw
Jul 1, 1990·Obstetrics and Gynecology·B TjadenJ A Rock
May 1, 1989·Fertility and Sterility·L FedeleG B Candiani
Oct 1, 1989·American Journal of Obstetrics and Gynecology·L FedeleG B Candiani
Mar 1, 1987·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·S TelimaaA Kauppila
Dec 1, 1987·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·S TelimaaA Kauppila
Sep 1, 1986·Fertility and Sterility·P L Matson, J L Yovich
May 2, 1987·British Medical Journal·E J Thomas, I D Cooke
Oct 1, 1988·Journal of in Vitro Fertilization and Embryo Transfer : IVF·S OehningerZ Rosenwaks
Feb 1, 1986·Fertility and Sterility·D L Olive
Jul 1, 1985·Fertility and Sterility·C F ChillikH W Jones
Mar 1, 1986·American Journal of Obstetrics and Gynecology·D L Olive, K L Lee
Nov 1, 1995·Fertility and Sterility·A B NamnoumJ A Rock
Aug 1, 1995·Fertility and Sterility·F OlivennesZ Rosenwaks
Mar 1, 1995·European Journal of Obstetrics, Gynecology, and Reproductive Biology·U CirkelH P Schneider
Nov 1, 1994·American Journal of Obstetrics and Gynecology·F ParazziniM Stella
May 1, 1994·British Journal of Obstetrics and Gynaecology·D K Edmonds, R Howell
Feb 1, 1996·The Australian & New Zealand Journal of Obstetrics & Gynaecology
Jun 1, 1996·Zhonghua yi xue za zhi = Chinese medical journal; Free China ed·S P Chang, H T Ng

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