PMID: 9187422Jan 1, 1997Paper

The treatment of pediatric lymphomas: paradigms to plagiarize?

Annals of Oncology : Official Journal of the European Society for Medical Oncology
I T Magrath

Abstract

The excellent results in pediatric lymphomas presented at the Sixth International Conference on Malignant Lymphoma in Lugano encompass several emerging themes and provide paradigms which it may be possible to extrapolate to at least some adult lymphomas. In pediatric Hodgkin's disease, there is mounting evidence that radiation adds nothing except toxicity to effective chemotherapy regimens, with the possible exception that patients with bulky disease, particularly in the mediastinum, may benefit from involved-field radiation. This is of particular importance in view of the recently recognized high rate of late-occurring second solid tumors and cardiac infarction, largely referable to radiotherapy. It is likely that there will be greater efforts to eliminate radiation from treatment protocols wherever possible. In pediatric non-Hodgkin's lymphomas, the intensive regimens used by several cooperative groups in Europe and the United States have resulted in very high event-free survival rates--90% in B-cell lymphomas, and only slightly lower in T-cell lymphomas. These results stand in striking contrast to those obtained in adults with the same diseases, except those treated with the same treatment protocols, who appear to have a sim...Continue Reading

Citations

Sep 3, 2010·International Journal of Endocrinology·Sunil Sharma, Mani Kavuru
Sep 7, 2012·Dermatology Research and Practice·Romain RoureChristiane Bertin
Aug 3, 2000·Cancer Investigation·P C BishopW H Wilson
Nov 5, 1997·Annals of the New York Academy of Sciences·I T Magrath
Feb 28, 2003·Annals of General Hospital Psychiatry·William E Reichman

❮ Previous
Next ❯

Related Concepts

Related Feeds

B-Cell Lymphoma

B-cell lymphomas include lymphomas that affect B cells. This subtype of cancer accounts for over 80% of non-Hodgkin lymphomas in the US. Here is the latest research.

Blood And Marrow Transplantation

The use of hematopoietic stem cell transplantation or blood and marrow transplantation (bmt) is on the increase worldwide. BMT is used to replace damaged or destroyed bone marrow with healthy bone marrow stem cells. Here is the latest research on bone and marrow transplantation.

Related Papers

Annals of Oncology : Official Journal of the European Society for Medical Oncology
S B Murphy, I T Magrath
Annals of Oncology : Official Journal of the European Society for Medical Oncology
S B Murphy
Critical Reviews in Oncology/hematology
L WhiteT C Quah
© 2021 Meta ULC. All rights reserved