Abstract
Objective. The purpose of our study was to understand the association between serum triglycerides and outcomes in acute ischemic stroke (AIS) patients. Methods. A cohort of all adult patients presenting to the Emergency Department (ED) with an AIS from March 2004 to December 2005 were selected. The lipid profile levels were measured within 24 hours of stroke onset. Demographics, admission stroke severity (NIHSS), functional outcome at discharge (modified Rankin Scale (mRS)), and mortality at 3 months were recorded. Results. The final cohort consisted of 334 subjects. A lower level of triglycerides at presentation was found to be significantly associated with worse National Institutes of Health Stroke Scale (NIHSS) (P = 0.004), worse mRS (P = 0.02), and death at 3 months (P = 0.0035). After adjusting for age and gender and NIHSS, the association between triglyceride and mortality at 3 months was not significant (P = 0.26). Conclusion. Lower triglyceride levels seem to be associated with a worse prognosis in AIS.
References
Apr 1, 1997·European Journal of Clinical Investigation·E T PoehlmanC J Rosen
May 7, 1998·Archives of Internal Medicine·R B Verdery, R L Walford
Aug 13, 1998·The American Journal of Clinical Nutrition·S E GariballaC M Castleden
Aug 6, 1999·Stroke; a Journal of Cerebral Circulation·G SulterJ De Keyser
Dec 12, 2001·Circulation·D TanneU Goldbourt
May 17, 2003·Stroke; a Journal of Cerebral Circulation·UNKNOWN FOOD Trial Collaboration
May 27, 2003·Cerebrovascular Diseases·Christopher J WeirKennedy R Lees
Jun 6, 2003·The Journal of Clinical Endocrinology and Metabolism·Molly C Carr
Jul 10, 2003·Lancet Neurology·Julien BogousslavskyUNKNOWN Board of Trustees, World Federation of Neurology
May 8, 2004·Stroke; a Journal of Cerebral Circulation·Tomasz DziedzicAndrzej Szczudlik
Oct 13, 2005·JAMA : the Journal of the American Medical Association·Margaret D CarrollClifford L Johnson
Oct 26, 2005·Neurology·Latha G SteadRobert D Brown
Apr 26, 2006·European Neurology·Slaven PikijaNedeljko Sokol
Mar 22, 2008·Neurocritical Care·Latha G SteadRobert D Brown
Apr 17, 2008·Advances in Therapy·Wei LiSong Tan
Jul 2, 2008·Clinical Chemistry and Laboratory Medicine : CCLM·Ana-Maria SimundicVida Demarin
Oct 29, 2008·Emergency Medicine Journal : EMJ·L G SteadR D Brown
Jan 28, 2009·Circulation·Donald Lloyd-JonesUNKNOWN American Heart Association Statistics Committee and Stroke Statistics Subcommittee
Nov 11, 2009·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Latha G SteadRobert D Brown
Jul 16, 2010·Atherosclerosis·Wi-Sun RyuByung-Woo Yoon
Dec 31, 2011·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Atsuhiro Kojima, Shunichi Okui
May 15, 2012·Journal of the Neurological Sciences·Kang-Ho ChoiKi-Hyun Cho
Citations
Jan 24, 2019·Lipids in Health and Disease·Tian-Li XiaDe-Jia Huang
May 24, 2020·International Journal of Molecular Sciences·Anna KloskaJoanna Jakóbkiewicz-Banecka
Oct 25, 2016·Metabolic Brain Disease·Konstantinos TziomalosApostolos I Hatzitolios
Jul 22, 2019·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Ivana CelapAna-Maria Simundic
Sep 10, 2020·Medicine·Zheng LiYun Luo
Dec 15, 2020·American Journal of Obstetrics and Gynecology·Maryam KazemiMarla E Lujan
Jan 19, 2021·Journal of Epidemiology·Aya HirataHirotsugu Ueshima
Aug 8, 2020·American Journal of Human Genetics·Allison MeisnerNilanjan Chatterjee
Jun 11, 2021·The American Journal of Cardiology·Julio A Lamprea-MontealegreIan H de Boer
Sep 10, 2021·BMC Cardiovascular Disorders·Fei LiJianzeng Dong