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The trithorax-group and polycomb-group chromatin modifiers: implications for disease

Current Opinion in Genetics & Development

Jun 23, 1999

M van Lohuizen

Abstract

The chromatin structure associated transcriptional memory function by Polycomb-group and trithorax-group protein complexes integrate normal development with control of cellular proliferation. This is illustrated by recent mechanistic insights that link Polycomb repression with histone d...read more

Mentioned in this Paper

Genes
Drosophila melanogaster Proteins
Histone Deacetylase
SPT6 Protein
Cell Proliferation
Cell Cycle
MLLT6
Polycomb-Group Proteins
PRC1 Complex Location
DNA Helix Destabilizing Proteins
Paper Details
References
  • References48
  • Citations45
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Polycomb group protein complexes: do different complexes regulate distinct target genes?

Biochimica Et Biophysica ActaSeptember 29, 1999
D P Satijn, A P Otte
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The trithorax-group and polycomb-group chromatin modifiers: implications for disease

Current Opinion in Genetics & Development

Jun 23, 1999

M van Lohuizen

PMID: 10377289

DOI: 10.1016/s0959-437x(99)80053-7

Abstract

The chromatin structure associated transcriptional memory function by Polycomb-group and trithorax-group protein complexes integrate normal development with control of cellular proliferation. This is illustrated by recent mechanistic insights that link Polycomb repression with histone d...read more

Mentioned in this Paper

Genes
Drosophila melanogaster Proteins
Histone Deacetylase
SPT6 Protein
Cell Proliferation
Cell Cycle
MLLT6
Polycomb-Group Proteins
PRC1 Complex Location
DNA Helix Destabilizing Proteins

Similar Papers Found In These Feeds

Parasite Genetics

Parasite genetics is the study of the genetic material of parasites. Here is the latest research on parasite genetics.

Nuclear Bodies: Biogenesis & Function

Nuclear bodies are membrane-less subnuclear organelles capable of affecting numerous nuclear functions from gene expression to rRNA biogenesis. They consist of the nucleoli, Cajal bodies, nuclear speckles, polycomb bodies, and paraspeckles. Discover the latest research on Biogenesis and Function of Nuclear Bodies here.

Paper Details
References
  • References48
  • Citations45
12345
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