The two-year course of late-life depression; results from the Netherlands study of depression in older persons

BMC Psychiatry
Hannie C ComijsMax L Stek

Abstract

We aimed to examine the course of depression during 2-year follow-up in a group clinically depressed older persons. Subsequently, we studied which socio-demographic and clinical characteristics predict a depression diagnoses at 2-year follow-up. Data were used from the Netherlands Study of Depression in Older persons (NESDO; N = 510). Diagnoses of depression DSM-IV-TR criteria were available from 285 patients at baseline and at 2-year follow-up. Severity of the depressive symptoms, as assessed with the Inventory of Depressive Symptoms (IDS), was obtained from 6-monthly postal questionnaires. Information about socio-demographic and clinical variables was obtained from the baseline measurement. From the 285 older persons who were clinically depressed at baseline almost half (48.4%) also suffered from a depressive disorder two years later. Patients with more severe depressive symptoms, comorbid dysthymia, younger age of onset and more chronic diseases were more likely to be depressed at 2-year follow-up. 61% of the persons that were depressed at baseline had a chronic course of depressive symptoms during these two years. Late-life depression often has a chronic course, even when treated conform current guidelines for older persons...Continue Reading

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Citations

Nov 8, 2015·Psychoneuroendocrinology·Fatima M KabiaHannie C Comijs
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Software Mentioned

NESDO
SPSS

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