The uniqueness of biobanks for neurological and psychiatric diseases: potentials and pitfalls.

Pathobiology : Journal of Immunopathology, Molecular and Cellular Biology
Rivka Ravid

Abstract

Central nervous system (CNS) biobanks are facing difficult and specific challenges due to the sensitive issue of collecting specimens of the CNS, and especially the brain. At present, there is no global network/central database to serve researchers, clinicians and pharma companies, or to supply the special specimens and the accompanying data in sufficient numbers and detail, respectively. The main challenge/objective is to standardize and harmonize all the facets involved in CNS biobanking in order to maximize efficient sample collection. Since the number of CNS biospecimens stored in existing biobanks is relatively limited and the accompanying data are not always readily available and hard to identify, we propose using optimal procedures for handling and storage of these specimens, and the global standardization of the cliniconeuropathological diagnostic criteria. One of the prominent achievements of the current global activity in brain tissue biobanks (BTB-banks) is the development of an inventory of international standards, available specimens and concomitant data, and national registries. Taking into consideration the huge variety of the specimens stored in different repositories and the enormous differences in medicolegal ...Continue Reading

Citations

Jul 5, 2017·Psychiatry and Clinical Neurosciences·Chun WuChun-Ting Lee
Oct 27, 2017·Health Technology Assessment : HTA·Charlotte L WilliamsNicholas Mp Clarke
Apr 30, 2017·BMC Complementary and Alternative Medicine·Yifang WangJinyong Xu

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