The Unmet Challenge of Medication Nonadherence

The Permanente Journal
Fred Kleinsinger

Abstract

Medication nonadherence for patients with chronic diseases is extremely common, affecting as many as 40% to 50% of patients who are prescribed medications for management of chronic conditions such as diabetes or hypertension. This nonadherence to prescribed treatment is thought to cause at least 100,000 preventable deaths and $100 billion in preventable medical costs per year. Despite this, the medical profession largely ignores medication nonadherence or sees it as a patient problem and not a physician or health system problem. Much of the literature on nonadherence focuses on barriers to adherence, with the assumption that appropriate adherence is the normal course of events and nonadherence is an aberration. This approach minimizes and oversimplifies the problem. It is not easy for humans to change their behavior, even for what many physicians see as a minor change such as taking prescription medications. Improving medication adherence has not been well studied, but a Cochrane review shows that multifactorial interventions are more effective. In at least one integrated health care system, Kaiser Permanente Northern California, a combination of approaches centered on the electronic health record has improved medication adhere...Continue Reading

Citations

Nov 12, 2019·Journal of Medical Internet Research·Anne-Françoise Audrain-PonteviaMyriam Ertz
Dec 11, 2019·International Journal of Public Health·Deivis Nicolas Guzman-TordecillaIvonne Rodríguez
Jul 21, 2020·Circulation. Cardiovascular Quality and Outcomes·John J WarnerUNKNOWN American Heart Association Partnering with Regulators Learning Collaborative*
Jun 13, 2020·Frontiers in Pharmacology·Grzegorz KardasPrzemysław Kardas
Oct 10, 2020·Clinical and Translational Allergy·Grzegorz KardasPrzemysław Kardas
May 26, 2021·JMIR MHealth and UHealth·Cristina JácomeJoão Almeida Fonseca
Jul 17, 2021·Clinical Journal of Oncology Nursing·Naomi Cazeau
Nov 7, 2021·Archives of Dermatological Research·Sung Kyung ChoBenjamin F Chong
Feb 3, 2022·The Annals of Pharmacotherapy·C Michael White

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