PMID: 7542833Aug 1, 1995Paper

The untreated patient with squamous carcinoma of the head and neck

American Journal of Clinical Oncology
A S Jones

Abstract

Of 3,482 patients with head and neck squamous carcinoma, 539 were unsuitable for radical treatment. Patients over 60 years of age were 1.6 times more likely not to receive radical treatment than younger patients. Patients who were unfit [Eastern Cooperative Oncology Group (ECOG) 1-4] were 1.4 times more likely not to receive radical treatment than those who were generally well. Patients with advanced primary tumours (T3, T4) were twice as likely to be considered unsuitable for radical treatment as patients with small tumours. Patients with neck node metastases were 2.1 times more likely to be considered unsuitable for radical treatment compared with those without nodes. In addition, if neck nodes were present their site influenced the decision to treat radically. Patients with disease low in the neck were 1.3 times more likely to be considered unsuitable for radical treatment than those with disease high in the neck. Survival for untreated patients was dismal. The median tumour specific survival was 5 months, and the 5-year survival was 4%. In contrast the 5-year survival for treated patients was 60%. Cox's regression on untreated patients showed that advanced age, poor general condition, and advanced nodal disease all adversel...Continue Reading

Citations

Apr 18, 2013·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Alfio FerlitoRobert P Takes
Oct 14, 2008·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Deepak KademaniUNKNOWN American Association of Oral and Maxillofacial Surgeons Task Force on Oral Cancer
Nov 6, 2008·Clinical Otolaryngology : Official Journal of ENT-UK ; Official Journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery·V Paleri, C G Kelly
Sep 10, 2005·Clinical Oncology : a Journal of the Royal College of Radiologists·J D RaguseH Oettle
Nov 16, 2016·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Hyo Geun ChoiSoon-Hyun Ahn
Dec 18, 2015·Dose-response : a Publication of International Hormesis Society·Peng ZhangC-M Ma
Mar 11, 2010·Expert Review of Anticancer Therapy·Claire McLarnonVinidh Paleri
Jan 15, 2014·Current Opinion in Otolaryngology & Head and Neck Surgery·Nicholas J Roland, Patrick J Bradley

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