PMID: 9192264Jun 1, 1997Paper

The uptake and acceptability to patients of cystic fibrosis carrier testing offered in pregnancy by the GP

Journal of Medical Genetics
N E HartleyR Harris

Abstract

To determine the uptake and acceptability of cystic fibrosis (CF) carrier testing when offered to women at the first antenatal booking appointment by their general practitioner. Eight-general practices in the north west region with a combined patient list size of 42000. Offer of carrier screening at first antenatal booking appointment to pregnant women below 14 weeks' gestation; women accepting were alternately allocated to either couple testing (with full disclosure) or stepwise testing: Six hundred and twenty three women were offered CF carrier testing. (1) Acceptance of the offer of CF carrier testing. (2) Acceptability of the test to women following screening, evaluated through (i) postal questionnaire, (ii) semistructured interview. Five hundred and twenty-nine (84.9%) women accepted the test; the level of uptake varied across the eight practices (range 11-99%). In 26/249 (10%) couple tests no paternal sample was provided. When asked what had influenced their decision to be tested, 59/377 (16%) women did not refer to CF in their answers and six (2%) said that they did not feel they could refuse the test. After receiving their results, 368/379 (97%) women felt that they had made the right decision to be tested, but two carr...Continue Reading

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Citations

Jan 26, 2002·Prenatal Diagnosis·Elizabeth DormandyTheresa M Marteau
Mar 25, 2005·Journal of Genetic Counseling·Elinor Langfelder-SchwindUNKNOWN National Society of Genetic Counselors Subcommittee on Cystic Fibrosis Carrier Testing
Aug 12, 2009·Journal of Religion and Health·Shulamis Juni Pollak
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Jun 1, 2004·Science in Context·N A Holtzman
Sep 14, 2013·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Liane IoannouMartin B Delatycki
Oct 19, 2006·Journal of Nursing Scholarship : an Official Publication of Sigma Theta Tau International Honor Society of Nursing·Sivia BarnoyMally Ehrenfeld
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Mar 12, 2010·The Australian & New Zealand Journal of Obstetrics & Gynaecology·Susannah MaxwellPeter O'Leary
May 20, 2000·The Journal of Perinatal & Neonatal Nursing·S A Demsey
Aug 5, 2000·American Journal of Medical Genetics·M HonnorJ Goldblatt
Aug 13, 2002·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Lidewij HennemanLeo P ten Kate
Sep 9, 2005·Health Education & Behavior : the Official Publication of the Society for Public Health Education·Catharine WangSharon L R Kardia
Aug 2, 2007·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Lei-Shih Chen, Patricia Goodson
Jul 2, 2003·American Journal of Medical Genetics. Part a·Claire GordonCarol Bower
Sep 21, 2007·Haemophilia : the Official Journal of the World Federation of Hemophilia·S ThomasP Komesaroff
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Mar 22, 2001·Genetics in Medicine : Official Journal of the American College of Medical Genetics·J E HaddowD R Witt

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