PMID: 3752165Oct 1, 1986Paper

The urine anion gap: a clinically useful index of ammonium excretion

The American Journal of the Medical Sciences
M B GoldsteinM L Halperin

Abstract

In patients with a normal plasma anion gap type of metabolic acidosis, knowledge of the rate of ammonium excretion can provide valuable information to determine if there is a renal cause for the disorder. Unfortunately, few hospital biochemistry laboratories offer routine determination of the urine ammonium concentration. Data are presented that demonstrate a direct linear relationship between the urine anion gap (Na+ + K+ - Cl-) and the urine ammonium concentration. In a 24-hour urine collection, the relationship is urine ammonium equals -0.8 (urine anion gap) +82 (r = 0.97 p less than 0.01). The applications of this index of ammonium excretion are discussed.

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Citations

May 1, 1990·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·J Rodríguez-Soriano, A Vallo
Mar 1, 1991·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·E J CarlisleM L Halperin
Aug 19, 2007·Indian Journal of Pediatrics·Arvind Bagga, Aditi Sinha
Feb 1, 1996·Disease-a-month : DM·M E Laski, N A Kurtzman
Oct 24, 2003·The American Journal of Emergency Medicine·Shih-Hua LinTom Chau
Mar 24, 2010·Nature Reviews. Nephrology·Jeffrey A Kraut, Nicolaos E Madias
Mar 12, 2005·QJM : Monthly Journal of the Association of Physicians·J H M GroeneveldM L Halperin
Sep 23, 2009·International Journal of Clinical Practice·P Reddy, A D Mooradian
Mar 10, 2012·Clinical Journal of the American Society of Nephrology : CJASN·Jeffrey A Kraut, Nicolaos E Madias
Feb 27, 2013·Indian Journal of Nephrology·R P GoswamiA Ghosh
Aug 1, 1989·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·R Krapf, M G Cogan
May 1, 1989·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·F J SilversteinC A Vaamonde
Aug 1, 1987·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·R M Richardson, M L Halperin
Aug 1, 1989·Kidney International·K KatagawaF Marumo
Dec 8, 2006·Seminars in Dialysis·Anton C SchoolwerthBrian D Remillard
Feb 1, 1991·Current Problems in Pediatrics·F SantosJ C Chan
Nov 6, 2014·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Daniel KittererJoerg Latus
Dec 19, 2013·The Journal of Pediatrics·Helena Gil-PeñaFernando Santos
Jan 8, 2015·The New England Journal of Medicine·Kenrick BerendRijk O B Gans
Jun 4, 2016·PloS One·Paolo BalsoranoAngelo Raffaele De Gaudio
Jan 17, 2017·Current Opinion in Pediatrics·Fernando SantosSilvia Alvarez-Alvarez
Jan 10, 2018·Clinical Journal of the American Society of Nephrology : CJASN·Daniel BatlleAlonso Marquez
May 22, 2010·Journal of the American Society of Nephrology : JASN·Mitchell L Halperin, Kamel S Kamel
Nov 4, 2017·Clinical Journal of the American Society of Nephrology : CJASN·Kalani L RaphaelJoachim H Ix
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Jun 20, 2013·CJEM·Jon Tuchscherer, Habib Rehman
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Jan 8, 2015·The New England Journal of Medicine·Aaron Spital
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Jul 14, 2019·Seminars in Nephrology·Wei ChenMatthew K Abramowitz
Jan 8, 2015·The New England Journal of Medicine·Mohamed A ShetaPaul Drawz
Mar 27, 2021·Journal of the American Society of Nephrology : JASN·Jaime Uribarri, Man S Oh
Apr 8, 2004·Disease-a-month : DM·William L Whittier, Gregory W Rutecki
Aug 24, 1999·Annals of Clinical Biochemistry·M D Penney, D A Oleesky
Jan 1, 1997·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·K S KamelM L Halperin
Oct 17, 2017·Advances in Chronic Kidney Disease·Glenn T Nagami, L Lee Hamm

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