The Urine Iodine to Creatinine as an Optimal Index of Iodine During Pregnancy in an Iodine Adequate Area in China

The Journal of Clinical Endocrinology and Metabolism
Chenyan LiWeiping Teng

Abstract

Iodine nutrition is a global event, especially for pregnant women. To develop applicable index of iodine intake for population during pregnancy. From 2012 to 2014, pregnant women at less than 8 weeks of gestation (n = 222) and reproductive-age women (n = 827) participated in this study. The pregnant women were evaluated at follow-up visits at 8, 12, 16, 20, 28, and 36 weeks of gestation and 3 and 6 months postpartum. Twenty-four-hour urine samples were collected at weeks 8 of gestation. Urine iodine (UI) and creatinine (Cr) and serum thyroglobulin were measured in all of the subjects. Circulatory iodine was measured using inductively coupled plasma-mass spectrometry at 8, 20, and 36 weeks of gestation and 6 months postpartum. The median UI concentration decreased from 183.6 to 104.2 μg/L during pregnancy. The serum iodine (SI) changes were similar to the UI to creatinine ratio (UI/Cr). The SI level was lowest at the eighth week of gestation (60.5 μg/L), which rose significantly until 20 weeks (106.5 μg/L) and then began to decline (36 wk, 84.7 μg/L). The 24-hour UI excretion measurement was regarded as the gold standard. The area under the receiver-operating characteristic curve for UI/Cr was 0.92 for iodine deficiency diagnose...Continue Reading

References

Aug 1, 1980·Kidney International·J M Davison, W Dunlop
Sep 1, 1997·The Journal of Clinical Endocrinology and Metabolism·P P SmythC O'Herlihy
Dec 29, 1998·Experimental and Clinical Endocrinology & Diabetes : Official Journal, German Society of Endocrinology [and] German Diabetes Association·P Bourdoux
Aug 14, 1999·Thyroid : Official Journal of the American Thyroid Association·D Glinoer
Jun 21, 2001·Experimental and Clinical Endocrinology & Diabetes : Official Journal, German Society of Endocrinology [and] German Diabetes Association·G JahreisM Leiterer
Dec 25, 2002·Clinical Biochemistry·Offie Porat Soldin
Aug 9, 2003·Journal of Endocrinological Investigation·L BranderH Gerber
Jun 3, 2005·Thyroid : Official Journal of the American Thyroid Association·P P A SmythJ H Lazarus
Jan 4, 2007·The Journal of Clinical Endocrinology and Metabolism·James E HaddowJoseph G Hollowell
Feb 21, 2008·The Journal of Clinical Endocrinology and Metabolism·Georgina StilwellJohn R Burgess
Sep 13, 2008·Clinical Endocrinology·Caterina MianMaria Elisa Girelli
Nov 4, 2008·Thyroid : Official Journal of the American Thyroid Association·Maria J CosteiraJoana A Palha
Dec 31, 2008·European Journal of Endocrinology·M Alvarez-PedrerolJ Sunyer
Jul 25, 2009·Endocrinología y nutrición : órgano de la Sociedad Española de Endocrinología y Nutrición·Begoña Peris RoigFrancisco Miralles Dolz
Nov 6, 2009·Thyroid : Official Journal of the American Thyroid Association·Pernille VejbjergTorben Jørgensen
May 26, 2010·Food and Nutrition Bulletin·Husref TahirovićDaniella Gnat
Apr 5, 2012·Nature Reviews. Endocrinology·Mu Li, Creswell J Eastman
Mar 16, 2013·Thyroid : Official Journal of the American Thyroid Association·Kathleen L CaldwellJohn Moye
Jun 19, 2013·Indian Journal of Endocrinology and Metabolism·Emmy GrewalNikhil Tandon
Sep 3, 2013·Journal of Trace Elements in Medicine and Biology : Organ of the Society for Minerals and Trace Elements (GMS)·Anibal AguayoItxaso Rica
Dec 7, 2013·Thyroid : Official Journal of the American Thyroid Association·Cria G PerrineChia-Yih Wang
Aug 5, 2014·Thyroid : Official Journal of the American Thyroid Association·Haixia LiuWeiping Teng
May 8, 2015·The American Journal of Clinical Nutrition·Sarah C BathMargaret P Rayman

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Citations

Oct 21, 2016·Thyroid : Official Journal of the American Thyroid Association·Sarah C BathMargaret P Rayman
Mar 13, 2018·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·Mallika VongchanaKuntharee Traisrisilp
Sep 16, 2018·Biological Trace Element Research·Wei ZhaoCheng Han
Dec 6, 2019·Thyroid : Official Journal of the American Thyroid Association·Caroline Serrano-NascimentoPilar Santisteban
Jan 8, 2020·Thyroid : Official Journal of the American Thyroid Association·Pantea NazeriMamak Shariat
Sep 2, 2020·Paediatric and Perinatal Epidemiology·Diane E ThreapletonDarren C Greenwood
Apr 18, 2019·Biological Trace Element Research·Zheng Feei Ma
Jan 28, 2020·Food & Nutrition Research·Solveig AdalsteinsdottirIngibjorg Gunnarsdottir
Jun 12, 2020·BMC Medicine·Charles Jonathan Peter SnartLaura J Hardie
May 5, 2020·Thyroid : Official Journal of the American Thyroid Association·Nathalie Silva de MoraisPatrícia Teixeira
May 1, 2017·European Journal of Nutrition·Ane Miren CastillaMarisa Rebagliato
Apr 10, 2021·Journal of Trace Elements in Medicine and Biology : Organ of the Society for Minerals and Trace Elements (GMS)·Ye BuYing Liu

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