The U.S. EPA Conference on Preventable Causes of Cancer in Children: a research agenda

Environmental Health Perspectives
M J CarroquinoP J Landrigan

Abstract

On 15-16 September 1997, the U.S. Environmental Protection Agency sponsored the Conference on Preventable Causes of Cancer in Children. The conference was convened to examine rising trends in reported incidence of childhood cancer and the association of these trends with environmental exposures. This paper summarizes recommendations for future research offered by participants. These recommendations included more collaborative research integrating epidemiology, molecular biology, toxicology, and risk assessment; the development of better protocols for toxicologic testing including carcinogenicity using young animals; and research focused on specific periods of development during which susceptibility to environmental agents may be enhanced. Also recommended was enhanced use and development of molecular biomarkers for identification of susceptible populations, and documentation of exposures and effects in epidemiologic and toxicologic studies. Although toxicologic testing is considered essential to determine the effects of potential carcinogens on biological organisms, participants emphasized the need to link these findings with epidemiologic and exposure assessment research.

References

Oct 1, 1990·The Journal of Clinical Endocrinology and Metabolism·B J SongP Saenger
Apr 1, 1989·Environmental Research·P A Schulte
Sep 15, 1988·Biochemical Pharmacology·L V Favreau, J B Schenkman
Jun 1, 1988·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·D TrizioN J Van Sittert
Nov 1, 1981·Clinical Pharmacology and Therapeutics·D K Manchester, E H Jacoby
Oct 15, 1981·International Journal of Cancer. Journal International Du Cancer·L TomatisV Ponomarkov
Jan 1, 1995·Journal of Occupational and Environmental Medicine·K Husgafvel-PursiainenH Vainio
Dec 1, 1994·Environmental Health Perspectives·E J O'Flaherty
May 1, 1994·The American Journal of Clinical Nutrition·W C Willett
Sep 1, 1995·Environmental Health Perspectives·R M Whyatt, F P Perera
Apr 17, 1996·Journal of the National Cancer Institute·F P Perera
Aug 1, 1996·Cancer·J G GurneyL L Robison
May 1, 1996·Environmental Health Perspectives·H Bartsch, E Hietanen
Feb 1, 1997·Environmental Health Perspectives·S S OlinG J Scarano
Nov 14, 1997·Science·F P Perera

❮ Previous
Next ❯

Citations

May 26, 1999·Environmental Health Perspectives·P A Buffler, A D Kyle
Jan 6, 2000·Environmental Health Perspectives·M C Hatch
Oct 22, 2011·Biological Trace Element Research·Yolanda Jasso-PinedaIván N Pérez-Maldonado
Apr 5, 2003·Toxicology Letters·Wolfgang Kaufmann
Jan 28, 2012·Environmental Science and Pollution Research International·Rebeca I Martínez-salinasFernando Díaz-Barriga
May 1, 2012·Environmental Science and Pollution Research International·Gabriela Domínguez-CortinasIván Nelinho Pérez-Maldonado
Dec 19, 2008·Chemosphere·Antonio Trejo-AcevedoIván N Pérez-Maldonado
Mar 10, 2009·Chemosphere·Iván N Pérez-MaldonadoFernando Díaz-Barriga
Apr 26, 2003·International Journal of Epidemiology·Julie Von Behren, Peggy Reynolds
Mar 15, 2005·Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals·William P Watson, Antonio Mutti
Aug 12, 2014·World Journal of Gastroenterology : WJG·Magdalena ChmielaKarolina Rudnicka
Sep 10, 2002·Journal of Toxicology. Clinical Toxicology·Philip J Landrigan, Anjali Garg

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.