PMID: 9552786Apr 29, 1998Paper

The use of 5% lidocaine for prolonged analgesia in chronic pain patients: a new technique

Regional Anesthesia and Pain Medicine
Y K Choi, J Liu

Abstract

It has been found that 5% lidocaine with 7.5% dextrose causes irreversible conduction block in animal studies. Our case report subjects allowed us to observe the efficacy of 5% lidocaine for a prolonged analgesia in vivo. After performing a diagnostic nerve block with 1% lidocaine, 5% lidocaine with 7.5% dextrose was injected into three patients with trigeminal neuralgia, post-herpetic occipital neuralgia, and intercostal neuralgia, respectively. The patients were followed for one and a half years. Visual Analog Scale (VAS) scores and the side effects were recorded for each patient. One patient received a trigeminal block and one patient received an occipital nerve block. Both patients reported immediate and complete pain relief lasting 14 and 8 months, respectively. One patient, given an intercostal nerve block, received immediate pain relief lasting 5 weeks. None of these patients exhibited any appreciable side effects or complications. Our observations suggest that 5% lidocaine may be used safely and effectively for the purpose of prolonged analgesia in selected patients with intractable chronic pain syndromes.

Citations

Aug 10, 2000·Anesthesiology Clinics of North America·G M Freedman, R Peruvemba
Mar 7, 2002·Journal of Clinical Anesthesia·Katsushi DoiYoji Saito
Jul 20, 2002·Regional Anesthesia and Pain Medicine·Yasuhisa OkudaToshimitsu Kitajima
Mar 20, 2010·Anesthesia and Analgesia·Akifumi KanaiHirotsugu Okamoto
Dec 24, 2002·Drugs & Aging·Mahmood Ahmad, Charles Roger Goucke
Apr 14, 2018·The Cochrane Database of Systematic Reviews·Neil E O'ConnellBenedict M Wand
Mar 16, 2012·The Cochrane Database of Systematic Reviews·Adam HurlowStephen G Oxberry
Apr 15, 2014·The Cochrane Database of Systematic Reviews·Neil E O'ConnellLorraine H Desouza

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