The use of a lacertid lizard as a model for reptile ecotoxicology studies: part 2--biomarkers of exposure and toxicity among pesticide exposed lizards

Chemosphere
Maria José AmaralReinier M Mann

Abstract

As part of a wider study examining the impacts of corn pesticides on lacertid lizards in north-western Portugal, we examined various physiological, biochemical, and histological biomarkers of exposure and effect among field populations of Podarcis bocagei. Biomarkers included body condition index, standard metabolic rate, locomotor performance, parasitization, glutathione oxidative pathways and related enzyme activity, lipid peroxidation and liver and testis histology. Few of the various biomarkers investigated provided statistically significant evidence of toxic effect. However, using a weight of evidence approach, we conclude that pesticides are affecting lizards living in the vicinity of pesticide exposed corn agriculture sites. Lizards from these locations present a profile of animals under metabolic stress with reduced condition indices, increased standard metabolic rate, lower incidence of hepatocyte vacuolation, altered iron metabolism, increased activation of GSH oxidation pathways, and even increased prevalence of hemoparasites.

References

Jun 1, 1979·Analytical Biochemistry·H OhkawaK Yagi
Aug 23, 1976·Biochemical and Biophysical Research Communications·R A Lawrence, R F Burk
Nov 1, 1995·Bulletin of Environmental Contamination and Toxicology·U Ozelmas, M T Akay
Nov 30, 2002·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Marcelo Hermes-Lima, Tania Zenteno-Savín
May 1, 1995·Archives of Gerontology and Geriatrics·B S JenaB K Patnaik
Feb 9, 2006·Archives of Environmental Contamination and Toxicology·R R HolemLarry G Talent
Jun 22, 2006·Archives of Environmental Contamination and Toxicology·M B MurphyJ P Giesy
Aug 26, 2006·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Paloma A ValdiviaA Alonso Aguirre
Mar 22, 2007·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Sarah E DuRantLarry G Talent
Apr 19, 2008·Environmental Toxicology and Chemistry·Craig A McFarlandMark S Johnson
Jun 1, 1995·Avian Pathology : Journal of the W.V.P.A·S C CorkP H Stockdale
Sep 26, 2008·Parasite : Journal De La Société Française De Parasitologie·B Sures
Jun 3, 2009·Die Naturwissenschaften·Panayiotis PafilisEfstratios Valakos
Jun 9, 2009·Environmental Pollution·Reinier M MannScott P Wilson
Aug 13, 2009·Archives of Environmental Contamination and Toxicology·Sunny O AbarikwuEbenezer O Farombi
Apr 13, 2010·Environmental Pollution·Miia J Koivula, Tapio Eeva
Feb 1, 2003·Environmental Toxicology and Pharmacology·Ron van der OostNico P E Vermeulen
Oct 1, 1992·Oecologia·Richard P BrownJ R Speakman

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Citations

Aug 6, 2013·Integrated Environmental Assessment and Management·David B MayfieldAnne Fairbrother
May 18, 2016·Environmental Pollution·Valentin MingoNorman Wagner
Oct 31, 2017·Environmental Science and Pollution Research International·Raiza Menezes Venturim SalvadorDenise Coutinho Endringer
Feb 23, 2018·EFSA Journal·UNKNOWN EFSA Panel on Plant Protection Products and their Residues (PPR)Robert H Smith
Jun 26, 2020·Environmental Monitoring and Assessment·Jadna Maria SilvaEliza Maria Xavier Freire
May 23, 2021·Zoology : Analysis of Complex Systems, ZACS·Giulia SimbulaAntigoni Kaliontzopoulou
Jun 28, 2021·Ecotoxicology·Giulia SimbulaLeonardo Vignoli
Oct 23, 2018·Journal of Agricultural and Food Chemistry·Huili WangJing Chang
Nov 11, 2021·Bulletin of Environmental Contamination and Toxicology·Emanuele FasolaClaudia Corti
Nov 23, 2021·The Science of the Total Environment·Jing ChangYinghuan Wang

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