The use of a "liquid" electrode in hepatic electrolysis

The Journal of Surgical Research
J G FinchG J Maddern

Abstract

The use of direct current electrolysis as a local nonthermal ablative technique for colorectal liver metastases promises to be a simple, safe, and effective therapy. Under general anesthesia, electrolysis is presently limited to tumors smaller than 5 cm, due to the protracted nature of its administration. In an attempt to enhance the effect of electrolysis, a direct current was passed through a preinjected bolus of acetic acid. The effect of a combination of electrolysis and an injection of acetic acid was tested in the liver of eight normal pigs. The volumes of necrosis caused were analyzed. Acetic acid independently produced a volume of necrosis but did not provide a volumetric or rate advantage when used in combination with a direct current. Statistically, the only main effect on the volume of necrosis was a result of electrolysis. The use of 50% acetic acid to augment the efficacy of direct current electrolysis cannot be recommended.

References

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Aug 17, 2000·The Australian and New Zealand Journal of Surgery·S A Wemyss-HoldenG J Maddern
Aug 18, 2000·The Journal of Surgical Research·S A Wemyss-HoldenG J Maddern

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Citations

Nov 18, 2005·The Journal of Surgical Research·Gernot M KaiserChristoph E Broelsch
Jun 9, 2016·Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine·Nikhilesh AnandSanjit Anand

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