The use of a novel adhesive tissue patch as an aid to anastomotic healing

Annals of the Royal College of Surgeons of England
J TrotterJ MacFie

Abstract

Introduction One of the most feared complications of colorectal surgery is anastomotic leak. Numerous techniques have been studied in the hope of decreasing leakage. This study was designed to assess the handling characteristics of a novel adhesive tissue patch (TissuePatch™; Tissuemed, Leeds, UK) applied to colorectal anastomoses in a pilot study. This was with a view to assessing its potential role in aiding anastomotic healing in subsequent trials. Methods A patch was applied to colorectal anastomoses after the surgeon had completed the anastomosis and prior to abdominal closure. Handling characteristics and patient outcomes were recorded prospectively. Results Nine patients were recruited before the study was prematurely terminated. In one patient, the patch fell off and in another patient, the surgeon omitted to apply it. Six patients had significant postoperative problems (1 confirmed leak necessitating return to theatre and excision anastomosis, 3 suspicious of leak on computed tomography delaying discharge, 2 perianastomotic collections). One patient had an uneventful recovery. Conclusions Although the handling characteristics of this novel tissue patch were deemed satisfactory, it appears that wrapping a colorectal ana...Continue Reading

References

May 1, 1995·Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research·M MedinaS D Schwaitzberg
Oct 8, 2003·Diseases of the Colon and Rectum·David E BeckUNKNOWN Adhesion Study Group Steering Committee
Jan 26, 2011·Techniques in Coloproctology·S GiuratrabocchettaD F Altomare
Mar 2, 2011·Langenbeck's Archives of Surgery·Martin ChmelnikStefan Holland-Cunz
Oct 11, 2011·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Holly K SheldonJames M Becker
Nov 15, 2011·British Journal of Neurosurgery·Christian von der BrelieHans Rainer Clusmann
Nov 15, 2011·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Tony VuocoloChristopher M Elvin
May 22, 2013·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Benjamin D ShoganKonstantin Umanskiy
Jun 15, 2013·International Journal of Colorectal Disease·Annelien N MorksUNKNOWN C-seal Study Group
Mar 5, 2014·Langenbeck's Archives of Surgery·Bernhard W RenzReinhold A Lang
May 11, 2017·The British Journal of Surgery·I S BakkerUNKNOWN Collaborative C-seal Study Group

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Citations

May 22, 2021·Indian Journal of Gastroenterology : Official Journal of the Indian Society of Gastroenterology·Mehmet Aykut YıldırımMustafa Şentürk
Jun 4, 2021·Advanced Healthcare Materials·Neta ShimonyBoaz Mizrahi

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