The use of a patency capsule in pediatric Crohn's disease: a prospective evaluation.

Digestive Diseases and Sciences
Stanley A CohenTamara Wakhisi

Abstract

Capsule endoscopy (CE) retention remains a concern in patients with suspected or known Crohn's Disease (CD). The aim of this study was to evaluate the ability of a patency capsule (PC) to establish functional patency in pediatric patients with suspected or known, symptomatic IBD. A prospective, single center study evaluating the impact of CE on CD management used PC to qualify patients for CE. Patients excreting an intact PC, usually within 40 h of ingestion, were able to undergo standard video CE. Excretion time, structural integrity and patient safety were evaluated. Eighteen patients (10-16 years of age; 9 male; 5 known CD, 3 indeterminate colitis, 1 ulcerative colitis, 9 suspected CD) ingested the PC. Fifteen patients excreted intact PC (mean 34.5 h), 12 patients within 40 h (range 9-60 h). Sixteen (89%) underwent subsequent CE successfully. CD was eventually diagnosed in all patients having PC transit ≥40 h, whereas CD was the diagnosis in 9/12 (75%) in those patients who passed the PC within 40 h. The mean time of passage for an intact PC was 34.7 h, the longest 60 h. There were no capsule retentions or adverse events. The PC appears to be a useful screening tool for functional patency of the small bowel in suspected or k...Continue Reading

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Citations

Apr 4, 2017·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Hironori YamamotoKazuma Fujimoto
Mar 11, 2017·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·J VialaA Lachaux
Mar 14, 2018·Therapeutic Advances in Gastroenterology·Artur NemethErvin Toth
May 3, 2018·Inflammatory Bowel Diseases·Ioannis V MitselosDimitrios Christodoulou
Jul 17, 2013·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Christian SchulzPeter Malfertheiner
Dec 4, 2014·World Journal of Gastroenterology : WJG·Salvatore OlivaEmanuele Casciani
Dec 27, 2016·World Journal of Gastroenterology : WJG·Dirk BandorskiMartin Keuchel
Jul 16, 2011·Journal of Pediatric Gastroenterology and Nutrition·Stanley A CohenBenjamin D Gold
Nov 16, 2013·Journal of Pediatric Gastroenterology and Nutrition·Arie LevineUNKNOWN European Society of Pediatric Gastroenterology, Hepatology, and Nutrition
Dec 17, 2015·Revista Española De Enfermedades Digestivas : Organo Oficial De La Sociedad Española De Patología Digestiva·Federico Argüelles-AriasCarmen Ribes-Koninckx
May 30, 2019·Journal of Clinical Biochemistry and Nutrition·Takeru OkuhiraHiroshi Tamai
Apr 10, 2021·Digestive Diseases and Sciences·Carlo CalabreseNico Pagano

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