Jan 1, 1976

The use of a single venous blood sample to assess oxygen binding in haemoglobin

British Journal of Haematology
M A LichtmanM Pogal


The measurement of pH, PO2, PCO2 and SO2 in a single venous blood sample can be used to determine the P50 at standard or at in vivo conditions. This technique makes it feasible for a physician, firstly, to make an assessment of the net adaptation of the red cell to reductions in blood oxygen content or flow and, secondly, to make an initial assessment of whether a haemoglobin with altered affinity for oxygen is present in subjects with polycythaemia or anaemia.

Mentioned in this Paper

Collection of Blood Specimen for Laboratory Procedure
Study, Methodological
Anemia, Sickle Cell
Umbilical Cord Blood
Myocardial Failure
Metabolic Acidosis
Hydrogen-Ion Concentration

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