PMID: 8604250Feb 1, 1996Paper

The use of allozyme electrophoresis to assess genetic heterogeneity among previously subspeciated isolates of Fusobacterium nucleatum

Oral Microbiology and Immunology
M L MorrisA H Rogers

Abstract

Fusobacterium nucleatum has been implicated in the pathogenesis of periodontal diseases. Five subspecies have previously been proposed. The validity of these subdivisions was investigated using allozyme electrophoresis for 21 enzyme mobilities. The 18 F. nucleatum isolates tested had previously been subspeciated and included type strains as well as isolates from both oral and extraoral sites. The results showed 2 distinct genetic groups with fixed differences at 82.5% of the test loci, indicative of a species complex with a number of subspecies within each of the 2 groups. There was also evidence of a correlation between the 2 major groups of isolates and the site from which they were taken. It was concluded that there is a high degree of genetic heterogeneity within the species F. nucleatum and that its current subspeciation is of questionable validity.

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Citations

Apr 30, 1999·International Journal for Parasitology·R H Andrews, N B Chilton
Jun 5, 1998·Australian Dental Journal·A H Rogers
Sep 19, 2009·Plasmid·Brianna M ClaypoolSusan Kinder Haake
Oct 21, 2016·Journal of Periodontology·Şivge KurganAlpdogan Kantarci
Mar 6, 1998·Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists·G H Bowden, I R Hamilton
Nov 15, 2014·The American Journal of Chinese Medicine·Yu LiuJinglai Qu
Jan 15, 2014·The Journal of Oral Implantology·James L Rutkowski
Jun 10, 1998·Journal of Biomedical Materials Research·S Szmukler-MonclerJ H Dubruille
Jul 9, 1999·Journal of Biomedical Materials Research·J A ParrW E Roberts
Mar 10, 1998·Journal of Biomedical Materials Research·D E SteflikD J Berkery
Aug 20, 2016·Genome Biology and Evolution·Mia Yang AngSiew Woh Choo

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