The use of ambulatory monitoring in the prognostic evaluation of patients with sustained ventricular tachycardia treated with amiodarone

Circulation
E P VeltriP R Reid

Abstract

We recently reported a retrospective experience with serial Holter monitoring as a guide to therapy in patients with sustained ventricular tachycardia treated with amiodarone. To confirm and substantiate these findings, a prospective study was designed that included baseline 24 hr Holter monitoring and serial Holter monitoring after 1 week of therapy with amiodarone. Fifty-two patients with documented sustained ventricular tachycardia who manifest nonsustained ventricular tachycardia on baseline Holter monitoring were treated with amiodarone. Thirty-four patients (group I) had nonsustained ventricular tachycardia completely suppressed and 18 patients (group II) had continued nonsustained ventricular tachycardia on serial Holter monitoring performed on days 8, 9, and 10 of therapy. At 11.6 +/- 1.0 (mean +/- SE) months follow-up, three (9%) group I patients and 12 (67%) group II patients had recurrent sustained ventricular tachycardia or sudden cardiac death (p less than .01). The sensitivity, specificity, positive and negative predictive value, and predictive accuracy of ventricular tachycardia on 24, 48, and 72 hr Holter monitoring over days 8, 9, and 10 for predicting recurrent sustained ventricular tachycardia or sudden cardi...Continue Reading

References

Dec 1, 1976·The American Journal of Cardiology·M B RosenbaumM V Elizari
Aug 1, 1976·The American Journal of Cardiology·H J WellensD Durrer
Mar 1, 1985·The American Journal of Cardiology·F E MarchlinskiM E Josephson
Aug 1, 1974·The American Journal of Cardiology·M B RosenbaumM V Elizari
Aug 1, 1970·British Journal of Pharmacology·B N Singh, E M Vaughan Williams
Jun 1, 1983·International Journal of Cardiology·S SaksenaG Cappello
Dec 1, 1983·Journal of the American College of Cardiology·H L GreeneG B Trobaugh
Jun 1, 1984·The American Journal of Cardiology·B McGovernJ N Ruskin
May 1, 1983·Annals of Internal Medicine·K NademaneeJ L Weiss
Jun 16, 1983·The New England Journal of Medicine·C D SwerdlowJ W Mason
Oct 1, 1982·Annals of Internal Medicine·J P DimarcoJ N Ruskin

❮ Previous
Next ❯

Citations

Apr 1, 1992·The American Journal of Cardiology·D NewmanJ C Griffin
Mar 1, 1989·Clinical Cardiology·R J HabermanE P Veltri
Aug 13, 1987·The New England Journal of Medicine
Feb 1, 1989·Pacing and Clinical Electrophysiology : PACE·A H KadishM E Josephson
May 11, 1991·Pacing and Clinical Electrophysiology : PACE·L Watkins, E Taylor
Dec 1, 1989·Pacing and Clinical Electrophysiology : PACE·E P Veltri
Mar 1, 1988·Pacing and Clinical Electrophysiology : PACE·E P VeltriM Mirowski

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antiarrhythmic Agents: Mechanisms of Action

Understanding the mechanism of action of antiarrhythmic agents is essential in developing new medications as treatment of cardiac arrhythmias is currently limited by the reduced availability of safe and effective drugs. Discover the latest research on Antiarrhythmic Agents: Mechanism of Action here.

Cardiology Journals

Discover the latest cardiology research in this collection of the top cardiology journals.

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.