The use of benzodiazpines and related drugs amongst older people in Sweden: associated factors and concomitant use of other psychotropics

International Journal of Geriatric Psychiatry
Kristina Johnell, J Fastbom

Abstract

To determine the factors associated with use of benzodiazepines and benzodiazepine related drugs (BZDs/BZDRDs) in a nationwide population of older people. We analyzed data on age, sex, type of residential area (urban/rural), and dispensed drugs for people aged > or = 75 years registered in the Swedish Prescribed Drug Register from October to December 2005 (n = 731,105; corresponds to 91% of the domain population). Multivariate logistic regression analysis was used for analyzing whether age, sex, type of residential area, number of other drugs, and concomitant psychotropic drug use was associated with use of BZDs/BZDRDs. > or =1 BZDs/BZDRDs and > or =2 BZDs/BZDRDs were used by 25% and 5% of the study population, respectively. The most commonly used BZDs/BZDRDs were zopiclone, zolpidem, oxazepam, flunitrazepam, and diazepam. The probability of use BZDs/BZDRDs increased with age, female gender, living in an urban area, use of many other drugs, and concomitant use of other psychotropics, particularly antidepressants. In the comparisons of different BZDs/BZDRDs (n = 179,632), the medium-acting BZDs were associated with higher age, female gender, and use of other psychotropics, whereas BZDRDs showed the opposite pattern. Also, the tw...Continue Reading

References

Dec 1, 1992·Journal of Clinical Psychopharmacology·W A Ray
Jan 1, 1991·Journal of Substance Abuse Treatment·M H Closser
Mar 1, 1990·Scandinavian Journal of Primary Health Care·G TibblinL Lapidus
Jan 1, 1994·Drugs & Aging·R I Shorr, D W Robin
May 1, 1997·Journal of Clinical Epidemiology·H S LauA Porsius
Nov 5, 1998·Lancet·F BarboneT M MacDonald
Jan 1, 1999·Clinical Pharmacology and Therapeutics·J T HanlonH J Cohen
Jan 13, 1999·International Journal of Geriatric Psychiatry·K OpedalE Eide
Feb 2, 1999·The British Journal of Psychiatry : the Journal of Mental Science·S TaylorJ R Copeland
Apr 5, 2000·Harvard Review of Psychiatry·G S Zubenko, T Sunderland
Sep 23, 2000·Journal of Geriatric Psychiatry and Neurology·M D LlorenteM A Silverman
Oct 30, 2001·American Journal of Epidemiology·S SchneeweissR J Glynn
Jan 17, 2002·The Annals of Pharmacotherapy·M R Brodeur, A L Stirling
Feb 15, 2002·Journal of the American Geriatrics Society·P S WangJ Avorn
Apr 10, 2002·American Journal of Therapeutics·Lisa B SignorelloWilliam J Blot
Sep 5, 2002·International Journal of Geriatric Psychiatry·Rachel MaidmentCornelius Katona
Mar 1, 2003·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Mario Giovanni TerzanoLiborio Parrino
Jun 6, 2003·International Journal of Geriatric Psychiatry·T LinjakumpuR Isoaho
Aug 19, 2003·CNS Drugs·Robert G Cumming, David G Le Couteur
Mar 6, 2004·Psychiatric Services : a Journal of the American Psychiatric Association·Olivera J Bogunovic, Shelly F Greenfield
Sep 1, 2004·Expert Opinion on Drug Safety·Subramoniam Madhusoodanan, Olivera J Bogunovic
May 20, 2005·Occupational and Environmental Medicine·L HardellK Hansson Mild
Nov 15, 2005·BMJ : British Medical Journal·Jennifer GlassUsoa E Busto
Feb 8, 2006·Journal of the American Geriatrics Society·Shelly L GrayDave M Buchner
Jun 8, 2007·European Journal of Clinical Pharmacology·Marie-Laure LarocheLouis Merle
Jun 28, 2007·The Annals of Pharmacotherapy·Kristina JohnellAndrejs Leimanis
Jul 25, 2007·International Journal of Geriatric Psychiatry·Hugo LövheimYngve Gustafson
Aug 30, 2007·Australian and New Zealand Journal of Public Health·Alice WindleVivienne Moore
Dec 7, 2007·International Journal of Geriatric Psychiatry·Jur-Shan ChengYaw-Tang Shih
Jan 1, 2008·The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry·James K WalshThomas Roth

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Citations

May 3, 2011·European Journal of Clinical Pharmacology·Kristina Johnell, Johan Fastbom
Oct 6, 2010·Pharmacy World & Science : PWS·Vesna Bacic-VrcaDario Rahelic
Jul 7, 2011·International Journal of Clinical Pharmacy·Kristina Johnell, Johan Fastbom
Sep 15, 2010·International Psychogeriatrics·Maria RikalaSirpa Hartikainen
Apr 1, 2010·The British Journal of General Practice : the Journal of the Royal College of General Practitioners·Andrea LasserreThomas Hanslik
Feb 5, 2014·The British Journal of Psychiatry : the Journal of Mental Science·Rebecca L GouldRobert J Howard
Jul 25, 2013·Research in Social & Administrative Pharmacy : RSAP·Yu-Chieh Chen, David H Kreling
Jul 29, 2010·Pharmacoepidemiology and Drug Safety·Falk HoffmannGerd Glaeske
May 18, 2013·International Journal of Methods in Psychiatric Research·Maria RikalaMaarit Jaana Korhonen
May 27, 2015·International Clinical Psychopharmacology·Heidi TaipaleSirpa Hartikainen
Mar 10, 2015·Aging & Mental Health·Guilhème PérodeauKieron O'Connor
May 9, 2012·Mayo Clinic Proceedings·Chia-Hung KaoChih-Hsin Muo
Apr 27, 2016·International Journal of Geriatric Psychiatry·Kristina JohnellPeter Salmi
Oct 22, 2011·Journal of Women & Aging·Guilhème PérodeauEmilie Grenon
Jan 23, 2019·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Hans WoutersKatja Taxis
Oct 9, 2019·International Journal of Clinical Pharmacy·Marija Delaš AždajićDanijela Štimac Grbić
Dec 13, 2018·European Archives of Psychiatry and Clinical Neuroscience·Arnaud PanesAnnie Fourrier-Réglat
Jul 10, 2017·British Journal of Clinical Pharmacology·Jonathan BrettSallie-Anne Pearson
Sep 4, 2020·British Journal of Clinical Pharmacology·Jonathan BrettNicholas A Buckley

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