The use of capsaicin in loin pain-haematuria syndrome

BJU International
Christopher C UzohAnthony G Timoney

Abstract

To highlight the implications of the use of capsaicin in managing loin pain-haematuria syndrome (LPHS). Between February 2002 and February 2007, three patients (one male and two females; mean age 31.7 years) with LPHS were managed with capsaicin and followed up for a period of 8-48 months. All were diagnosed with LPHS after negative urological investigations including urine culture, urine cytology, renal tract ultrasonography, intravenous urography and flexible cystoscopy; and nephrological work-ups including normal blood pressure measurements, creatinine clearance, urinary protein estimation and serum urea/creatinine. Five original papers were reviewed in detail for this article. Including our own experience, a total of 52 (including five bilateral) cases of LPHS treated with capsaicin are reviewed. Our patients received a total of four capsaicin instillations producing an average duration of pain relief per instillation of 17 weeks. There was evidence of renal deterioration in one, while another had worsened symptoms. The third patient continued his pain management within the pain clinic. The former two patients eventually underwent nephrectomy for poor function and extreme symptoms. Intrarenal capsaicin at best produces only...Continue Reading

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Citations

Jun 7, 2013·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Esther de BeusCarmine Zoccali
Apr 15, 2014·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Sahar Taba Taba VakiliHans Sollinger
Jun 16, 2012·The Clinical Journal of Pain·Howard S Smith, Zahid H Bajwa
Jan 23, 2016·Clinical Kidney Journal·Adeel S ZubairMikel Prieto
Aug 17, 2016·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Bhanu PrasadJennifer Rose St Onge
Apr 23, 2016·The Korean Journal of Pain·Andrew Kristian Grech
Mar 28, 2019·Journal of Cellular Physiology·Reza Alizadeh, Ziba Aghsaie Fard
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Jan 27, 2021·Current Pain and Headache Reports·Ivan UritsAlan D Kaye
Nov 1, 2020·Current Hypertension Reports·Leslie Marisol Lugo-GavidiaMarkus P Schlaich

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