The use of computed tomography images as a prognostic marker in critically ill cancer patients

Clinical Nutrition ESPEN
Diogo O ToledoJoao M Silva

Abstract

In the intensive care unit (ICU) setting, body composition is typically estimated through anthropometry, which does not specifically quantify skeletal muscle (SM). Recent findings have shown that computed tomography (CT) is a useful tool to identify low SM in critically ill patients, which in turn is associated with poor clinical outcomes. So, the present study aims at comparing low SM assessed by CT to BMI anthropometric data and its association with outcomes in critically ill patients. Observational study was used, which included >18 year-old patients, with over 72 h of ICU length of stay, who had an abdominal CT at ICU admission. Demographic, body mass index (BMI), hospital outcomes and abdominal CT data (SM and adipose tissue at the 3rd lumbar vertebrae) were collected for analysis. ROC curve optimal stratification analysis for hospital mortality was applied to classify people into low SM (sarcopenic) versus normal SM (non-sarcopenic). A Cox regression was applied to find independent associations between sarcopenia and 30-day survival. The study involved 99 patients, 56% male, mean-age of 61.6 years old, BMI 24.19 ± 4.49 kg/m2; hospital mortality was 26%. According to BMI, 19.4% of the patients were underweight. However, a ...Continue Reading

Citations

Jan 17, 2020·Plastic and Reconstructive Surgery. Global Open·Travis J MillerArash Momeni
Jan 23, 2021·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·Anja Bosy-Westphal, Manfred J Müller
Feb 16, 2021·American Journal of Physical Medicine & Rehabilitation·Paulina Moctezuma-VelázquezCarlos Moctezuma-Velázquez
Dec 2, 2020·Journal of Renal Nutrition : the Official Journal of the Council on Renal Nutrition of the National Kidney Foundation·André V BichelsMaria A Kamimura

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