The use of HIV post-exposure prophylaxis in forensic medicine following incidents of sexual violence in Hamburg, Germany: a retrospective study

Forensic Science, Medicine, and Pathology
Julia EbertAnn Sophie Schröder

Abstract

In Hamburg, Germany, the initiation of HIV post-exposure prophylaxis (HIV PEP) in cases of sexual violence is often carried out by forensic medical specialists (FMS) using the city's unique Hamburg Model. FMS-provided three-day HIV PEP starter packs include a combination of raltegravir and emtricitabine/tenofovir. This study aimed to investigate the practice of offering HIV PEP, reasons for discontinuing treatment, patient compliance, and whether or not potential perpetrators were tested for HIV. We conducted a retrospective study of forensic clinical examinations carried out by the Hamburg Department of Legal Medicine following incidents of sexual violence from 2009 to 2016. One thousand two hundred eighteen incidents of sexual violence were reviewed. In 18% of these cases, HIV PEP was initially prescribed by the FMS. HIV PEP indication depended on the examination occurring within 24 h after the incident, no/unknown condom use, the occurrence of ejaculation, the presence of any injury, and the perpetrator being from population at high risk for HIV. Half of the HIV PEP recipients returned for a reevaluation of the HIV PEP indication by an infectious disease specialist, and just 16% completed the full month of treatment. Only 13...Continue Reading

References

Apr 10, 1997·The New England Journal of Medicine·R A RoyceM S Cohen
Apr 6, 2005·International Journal of STD & AIDS·David J TempletonR J Garsia
Jul 5, 2005·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·Judith A LindenColleen LaBelle
Jul 5, 2006·Archives of Pediatrics & Adolescent Medicine·Elyse OlshenCathryn L Samples
Jun 2, 2007·BMJ : British Medical Journal·Jan Welch, Fiona Mason
Oct 30, 2009·The New England Journal of Medicine·Raphael J Landovitz, Judith S Currier
Apr 16, 2014·Western Journal of Nursing Research·Jessica E DraughonDaniel J Sheridan
May 2, 2014·Journal of Medical Primatology·Ellen N KershJanet McNicholl
Jul 2, 2014·Women's Health Issues : Official Publication of the Jacobs Institute of Women's Health·Kathleen H KrauseLindsey R Baden
May 15, 2015·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Nathan FordUNKNOWN World Health Organization Postexposure Prophylaxis Guideline Development Group
Dec 15, 2015·Nursing Research·Jessica E Draughon MoretDaniel J Sheridan

❮ Previous
Next ❯

Citations

Sep 18, 2021·Medizinische Klinik, Intensivmedizin und Notfallmedizin·Veit-Simon Eckle, Florian Alius

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

JAMA : the Journal of the American Medical Association
J E MylesJ D Bamberger
© 2022 Meta ULC. All rights reserved