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The use of hybrid molecules in a study of the equilibrium between nerve growth factor monomers and dimers

Neurobiology

Dec 1, 1975

Jonathan Moore, Eric M Shooter

PMID: 1691

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Abstract

The major protein in beta nerve growth factor preparations, beta1NGF, is a dimer in which both peptide chains have COOH-terminal arginine residues. Digestion of beta1NGF with carboxypeptidase B produced a dimer, beta3NGF, in which both chains lack these terminal arginine residues. Expos...read more

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Arginine hydrochloride
Hydrogen-Ion Concentration
Half-Life
Carmol
Isoelectric Focusing
Peptide Chain Termination, Translational
Neurite Outgrowth Factors
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  • The use of hybrid molecules in a study of the equilibrium between nerve growth factor monomers and dimers

    Neurobiology

    Dec 1, 1975

    Jonathan Moore, Eric M Shooter

    PMID: 1691

    DOI:

    Abstract

    The major protein in beta nerve growth factor preparations, beta1NGF, is a dimer in which both peptide chains have COOH-terminal arginine residues. Digestion of beta1NGF with carboxypeptidase B produced a dimer, beta3NGF, in which both chains lack these terminal arginine residues. Expos...read more

    Mentioned in this Paper

    Arginine hydrochloride
    Hydrogen-Ion Concentration
    Half-Life
    Carmol
    Isoelectric Focusing

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