The use of ibuprofen and acetaminophen for acute headache in the postconcussive youth: A pilot study

Paediatrics & Child Health
Tina PetrelliSheila K Singh

Abstract

Acute postconcussive headaches are problematic for children after mild traumatic brain injury. There are no evidence-based guidelines for their management. This pilot study aims to assess the feasibility and efficacy of routine analgesia administration. A four-arm open-label randomized controlled trial pilot/feasibility study was conducted: (i) acetaminophen, (ii) ibuprofen, (iii) alternating acetaminophen and ibuprofen and (iv) a control group. Children and youth 8 to 18 years of age presenting to emergency department with headache within 48 hours of their first concussion were recruited consecutively and sequentially randomized. Children with abnormal neuroimaging, history of previous concussions and bleeding disorder were excluded. A headache survey was administered at recruitment. All participants were provided with standard concussion management education and were also instructed on how to use the headache diary for the 1-week study follow-up period. The diary captures (i) headache days, (ii) number of headaches, (iii) headache intensity and (iv) return-to-school information. Feasibility was assessed based on study recruitment and compliance. There were no feasibility concerns with the recruitment and no major compliance i...Continue Reading

References

Mar 19, 2003·The American Journal of Sports Medicine·Michael W CollinsFreddie H Fu
Jun 22, 2006·American Journal of Physical Medicine & Rehabilitation·Henry L LewWilliam C Walker
Jun 16, 2009·Journal of Pediatric Surgery·Thane A BlinmanMichael L Nance
Jul 28, 2010·Pediatrics·Karen Maria BarlowDeborah Dewey
Aug 19, 2010·The American Journal of Sports Medicine·William P MeehanR Dawn Comstock
Mar 1, 2012·PM & R : the Journal of Injury, Function, and Rehabilitation·Thomas K WatanabeKatherine Schomer
Oct 20, 2012·Current Opinion in Pediatrics·Meeryo C ChoeChristopher C Giza
Dec 28, 2012·Clinical Journal of Sport Medicine : Official Journal of the Canadian Academy of Sport Medicine·Kimberly G HarmonUNKNOWN American Medical Society for Sports Medicine
Jan 2, 2013·Paediatrics & Child Health·Laura K Purcell, UNKNOWN Canadian Paediatric Society, Healthy Active Living and Sports Medicine Committee
May 8, 2016·Physical Medicine and Rehabilitation Clinics of North America·Grant L Iverson, Gerard A Gioia

❮ Previous
Next ❯

Citations

Sep 7, 2018·Current Opinion in Pediatrics·Heidi K Blume
Sep 20, 2020·Current Neurology and Neuroscience Reports·Danny Adel MonsourAna Marissa Lagman-Bartolome
Sep 12, 2018·Current Pain and Headache Reports·Johna K Register-MihalikKevin Carnerio
Mar 5, 2021·Seminars in Neurology·Charles G WilberMohammad N Haider
Nov 28, 2020·The American Journal of Emergency Medicine·Louis StandifordChristopher Trigger
Nov 25, 2021·Current Neurology and Neuroscience Reports·John J LeddyBarry Willer
Dec 5, 2021·Headache·Carlyn Patterson GentileChristina L Szperka

❮ Previous
Next ❯

Related Concepts

Related Feeds

Brain Injury & Trauma

brain injury after impact to the head is due to both immediate mechanical effects and delayed responses of neural tissues.

Blood Clotting Disorders

Thrombophilia includes conditions with increased tendency for excessive blood clotting. Blood clotting occurs when the body has insufficient amounts of specialized proteins that make blood clot and stop bleeding. Here is the latest research on blood clotting disorders.