The use of intravenous and inhaled magnesium sulphate in management of children with bronchial asthma

The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
Waleed H Albuali

Abstract

Asthma is the most common chronic disease of childhood and the leading cause of childhood morbidity. When uncontrolled, asthma can place significant limits on daily life, and is sometimes fatal. The use of magnesium sulphate (MgSO4) is one of numerous treatment options available during acute severe asthma in children. The efficacy of intravenous, or inhaled MgSO4 has been demonstrated, while little is known about the actual clinical use of either intravenous (IV) or inhaled MgSO4. To assess the effectiveness of intravenous (IV) and/or inhaled MgSO4 on hospital admissions and pulmonary function in children with asthma. This systematic review assessed the best available evidence for the use of either intravenous or inhaled MgSO4 in children with acute asthma. Magnesium deficiency is a common electrolyte disorder in children with acute severe asthma. Several authors reported that IV magnesium was effective in the treatment of moderate to acute asthma in children but evidence for nebulised magnesium was insufficient. In addition, it is used in severe, progressed cases to prevent respiratory failure and/or admission to the intensive care unit. It has bronchodilating and anti-inflammatory effects and modulates ion transport and influ...Continue Reading

References

Sep 1, 1992·Annals of Emergency Medicine·V T Chande, D P Skoner
Nov 1, 1991·Annals of Emergency Medicine·L M Kuitert, S L Kletchko
Oct 1, 1990·Annals of Emergency Medicine·W H SpiveyR M Levin
Dec 1, 1990·Journal of the American College of Nutrition·W Wei, K B Franz
Jul 1, 1984·American Heart Journal·L T Iseri, J H French
May 1, 1995·American Journal of Respiratory and Critical Care Medicine·T C Corbridge, J B Hall
Mar 13, 1995·Archives of Internal Medicine·M S SkorodinN D'Alfonso
Dec 1, 1996·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·C B Cairns, M Kraft
Jan 1, 1997·Current Opinion in Pulmonary Medicine·R A Nicklas
Jan 6, 2000·European Journal of Emergency Medicine : Official Journal of the European Society for Emergency Medicine·F GürkanA Ece
Jan 21, 2000·Australian and New Zealand Journal of Public Health·L S PilottoR Mitchell
Mar 21, 2000·The American Journal of Medicine·L J NanniniR Quispe
Mar 23, 2000·Clinica Chimica Acta; International Journal of Clinical Chemistry·N E SarisA Lewenstam
Sep 2, 2000·Annals of Emergency Medicine·H J AlterW M Hilty
Nov 30, 2000·Annals of Emergency Medicine·R J ScarfoneE J Gracely
Apr 28, 2001·Annals of Emergency Medicine·J Li
Aug 13, 2002·Chest·Robert A SilvermanUNKNOWN Acute Asthma/Magnesium Study Group
Jan 16, 2003·Chest·Eleftherios ZervasStelios Loukides
Feb 21, 2004·BMJ : British Medical Journal·Christine JenkinsLinda Hodge
Dec 23, 2004·Archives of Disease in Childhood·D K L CheukS L Lee
Jan 22, 2005·Treatments in Respiratory Medicine·Sandra D Anderson
Jul 9, 2005·Chest·Maurice BlitzBrian H Rowe
Aug 11, 2005·Current Allergy and Asthma Reports·Marianne Frieri
Dec 2, 2005·Scandinavian Journal of Clinical and Laboratory Investigation·R SinertB M Altura
Jun 1, 2006·The Annals of Pharmacotherapy·Eric J Villeneuve, Peter J Zed
Jun 22, 2006·European Journal of Clinical Nutrition·C Gontijo-AmaralJ D Ribeiro
Feb 6, 2007·Archivum Immunologiae Et Therapiae Experimentalis·Aneta KowalAndrzej Obojski
Nov 22, 2007·Emergency Medicine Journal : EMJ·S Mohammed, S Goodacre
Nov 29, 2007·Current Opinion in Pulmonary Medicine·Brian H Rowe, Carlos A Camargo
May 24, 2008·Archives of Disease in Childhood·G DaviesW Lenney
Apr 16, 2009·Pediatrics·Fernando D Martinez

❮ Previous
Next ❯

Citations

Mar 1, 2017·Paediatric Anaesthesia·Ramón Eizaga RebollarLuis M Torres
Apr 8, 2018·Italian Journal of Pediatrics·Luciana IndinnimeoUNKNOWN Italian Panel for the management of acute asthma attack in children Roberto Bernardini
May 15, 2015·ERJ Open Research·Fabio MidullaErnst Eber
Feb 14, 2018·The European Respiratory Journal·Hannele PruikkonenMarjo Renko
Aug 23, 2019·Nihon eiseigaku zasshi. Japanese journal of hygiene·Masaru Sagai

❮ Previous
Next ❯

Related Concepts

Related Feeds

Asthma

This feed focuses in Asthma in which your airways narrow and swell. This can make breathing difficult and trigger coughing, wheezing and shortness of breath.

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.

Allergies & Environmental Factors

Environmental factors are strongly associated with the prevalence of allergies and are an increasing health concern worldwide. Discover the latest research on Allergies and Environmental Factors here.