The use of mesenchymal (skeletal) stem cells for treatment of degenerative diseases: current status and future perspectives

Journal of Cellular Physiology
Basem M Abdallah, Moustapha Kassem

Abstract

Human bone marrow derived-mesenchymal (skeletal) stem (MSC) cells are a group of non-hematopoietic stem cells residing in the perivascular niches in bone marrow. These cells have the capacity to differentiate mainly into mesoderm-type cells such as osteoblasts, chondrocytes and adipocytes and possibly but not proven to non-mesodermal cell types. Recently, there has been an increased interest in understanding the biology of MSC due to their potential use in cell-based therapy for multiple degenerative diseases. Here, we will provide an update on the current status of these novel therapeutic opportunities. J. Cell. Physiol. 218: 9-12, 2009. (c) 2008 Wiley-Liss, Inc.

References

Jan 1, 1979·Acta Haematologica·T M Dexter
Jun 1, 1989·Acta Orthopaedica Scandinavica·H OhgushiA I Caplan
Nov 1, 1971·Transfusion·E A LuriaA Y Friedenstein
Nov 1, 1994·Journal of Cellular Biochemistry·S P BruderA I Caplan
Dec 1, 1993·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·M KassemE F Eriksen
Mar 1, 1996·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·D J RickardB L Riggs
Sep 1, 1997·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·S A KuznetsovP G Robey
Mar 13, 1999·The Journal of Clinical Investigation·S MakinoS Ogawa
Apr 2, 1999·Science·M F PittengerD R Marshak
Feb 24, 2001·The New England Journal of Medicine·R QuartoM Marcacci
May 31, 2001·The Journal of Cell Biology·S A KuznetsovP G Robey
Aug 18, 2001·Arthritis and Rheumatism·C De BariF P Luyten
Nov 2, 2001·Nature·P Bianco, P G Robey
Feb 2, 2002·Experimental Hematology·Amelia BartholomewRonald Hoffman
Feb 6, 2002·The Journal of Clinical Investigation·Morayma ReyesCatherine M Verfaillie
Jun 25, 2002·The Annals of Thoracic Surgery·Jay G ShakeBradley J Martin
Jun 27, 2002·Proceedings of the National Academy of Sciences of the United States of America·Edwin M HorwitzTed Hofmann
Jul 24, 2002·Experimental Hematology·Nadia QuiriciGiorgio Lambertenghi Deliliers
Nov 29, 2002·Calcified Tissue International·C RosadaM Kassem
Apr 30, 2003·Proceedings of the National Academy of Sciences of the United States of America·Masako MiuraSongtao Shi
Jul 19, 2003·Clinical Oral Implants Research·Ingeborg J De KokLyndon F Cooper
Oct 11, 2003·Experimental Hematology·Katarina Le BlancOlle Ringdén
Jul 2, 2004·Experimental Biology and Medicine·Wenrong XuYongchang Chen
Jul 31, 2004·American Journal of Physiology. Heart and Circulatory Physiology·Noritoshi NagayaSoichiro Kitamura
Apr 6, 2005·Biochemical and Biophysical Research Communications·J F BentzonM Kassem
Apr 23, 2005·Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation·Hillard M LazarusAndrea Bacigalupo

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Citations

Jan 20, 2012·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Xiaozhou YingChuanzhu Lu
Feb 17, 2009·Biogerontology·Jan O Nehlin, Torben Barington
Dec 4, 2009·Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology·Dana FoudahGiovanni Tredici
Aug 14, 2013·Journal of Biosciences·Hamid Saeed, Mehwish Iqtedar
May 23, 2012·Stem Cells and Development·Amer MahmoodMoustapha Kassem
May 28, 2010·Tissue Engineering. Part a·Yash M KolambkarRobert E Guldberg
Aug 15, 2009·Current Opinion in Hematology·Alois Gratwohl, Helen Baldomero
Nov 16, 2011·European Journal of Endocrinology·Hanna TaipaleenmäkiMoustapha Kassem
May 23, 2014·Nature Materials·P C Dave P Dingal, Dennis E Discher
Jul 21, 2009·Current Opinion in Cell Biology·Rebeca M Tenney, Dennis E Discher
Jun 21, 2013·Pediatrics International : Official Journal of the Japan Pediatric Society·Takeshi TaketaniSeiji Yamaguchi
Mar 24, 2012·Journal of Cellular Biochemistry·Salla K LaineTiina K Laitala-Leinonen
Apr 27, 2011·Aging Cell·Shuanhu ZhouJulie Glowacki
Jul 13, 2011·Bone·Basem M Abdallah, Moustapha Kassem
May 11, 2013·Stem Cell Research·Stefanie LiedtkeGesine Kögler
Mar 17, 2016·Integrative Biology : Quantitative Biosciences From Nano to Macro·Miguel XavierOliver Otto
Mar 13, 2012·International Journal of Molecular Sciences·Gabriela CiapettiNicola Baldini
Nov 11, 2009·Nature Reviews. Rheumatology·Ericka M Bueno, Julie Glowacki
Nov 17, 2009·Expert Review of Medical Devices·Thomas HodgkinsonArdeshir Bayat
May 2, 2020·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Pere DostaNatalie Artzi
Aug 12, 2014·Molecular Medicine Reports·Xiao-Huang TuXiao-Li Yang
Nov 20, 2009·The Journal of Immunology : Official Journal of the American Association of Immunologists·Qunzhou ZhangAnh D Le
Nov 3, 2020·Stem Cells International·Takahiro TeshimaHidekazu Koyama
Feb 23, 2020·The International Journal of Biochemistry & Cell Biology·Jian WenLisheng Hu
Apr 17, 2021·The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology·Basem M Abdallah

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