The use of mutual information in registration of CT and MRI datasets post permanent implant

Brachytherapy
P William McLaughlinPeter L Roberson

Abstract

To determine the feasibility of registration of MRI and CT datasets post permanent prostate implant by the use of mutual information. Five patients who underwent permanent (125)I implant for prostate carcinoma were studied. Two weeks postimplant an axial CT, T2-weighted-axial, sagittal and coronal MRI, and T1-fat-saturation MRI scans were obtained. Registrations of MRI to CT and MRI to MRI datasets were performed by mutual information, an automated process of data registration matching all information in specified dataset regions of interest. Registration quality was evaluated by visual inspection, agreement with seed- to-seed registration, and histogram analysis. Rapid registration (<30 minutes) of CT and MRI datasets can be accomplished through the use of mutual information. All methods of registration evaluation confirmed excellent registration quality. Although D90 and V100 for the prostate were comparable between MRI- and CT-based dosimetry, dose to critical structures/microenvironments (anterior base, posterior base, bladder outlet, lower sphincter, bulbar urethra) defined on MRI varied widely. Efficient and accurate registration of MRI and CT datasets following prostate implant is possible, and improves the accuracy of p...Continue Reading

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Citations

Sep 20, 2005·International Journal of Radiation Oncology, Biology, Physics·Patrick W McLaughlinJames Montie
May 31, 2013·Medical Physics·Anne Sofie KorsagerLasse Riis Østergaard
Sep 19, 2006·The British Journal of Radiology·M L Kessler
Jul 24, 2013·Brachytherapy·Marisol De BrabandereFrank-André Siebert
Aug 4, 2012·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Marisol De BrabandereFrank-André Siebert
Nov 15, 2011·International Journal of Radiation Oncology, Biology, Physics·Eugene ChungPatrick W McLaughlin
Jun 7, 2011·International Journal of Radiation Oncology, Biology, Physics·Eugene ChungPatrick W McLaughlin
Jun 12, 2009·International Journal of Radiation Oncology, Biology, Physics·Patrick W McLaughlinVrinda Narayana
Jan 5, 2005·International Journal of Radiation Oncology, Biology, Physics·Patrick W McLaughlinMarc Kessler
Jan 5, 2005·International Journal of Radiation Oncology, Biology, Physics·Vrinda NarayanaPatrick W McLaughlin
Mar 28, 2006·International Journal of Radiation Oncology, Biology, Physics·Daniel TausskyJuanita Crook
Dec 14, 2005·Brachytherapy·Gregory S MerrickZachariah A Allen
Oct 26, 2005·International Journal of Radiation Oncology, Biology, Physics·Patrick McLaughlinPeter Roberson
Sep 3, 2005·International Journal of Radiation Oncology, Biology, Physics·Daniel R ReedWayne Butler
Apr 5, 2014·Journal of Magnetic Resonance Imaging : JMRI·Chaitanya KalavaguntaGregory J Metzger
Sep 28, 2018·Physics in Medicine and Biology·Evan McNabbMichael D Noseworthy
Mar 28, 2020·Journal of Applied Clinical Medical Physics·Samaneh KazemifarAmir Owrangi

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