PMID: 107936Oct 1, 1978

The use of parenteral nutrition in the management of external gastrointestinal tract fistulae

The Australian and New Zealand Journal of Surgery
R J Thomas, A Rosalion


Malnutrition is common in patients with gastrointestinal tract fistula, and is an important cause of the high mortality seen with this surgical complication. A prospective review of three years' experience in the management of fistulae with parenteral nutrition was undertaken, and the results obtained were compared with those in a group of patients treated prior to the introduction of this form of therapy. The use of parenteral nutrition resulted in a reduction of the mortality from 63% to 23% in unselected cases. The mortality was zero where parenteral nutrition was used in patients under 65 years of age with non-malignant disease. With parenteral nutrition therapy, the fistulae in almost all cases closed spontaneously, in contrast with a high proportion requiring operation (20 in 38 cases) where parenteral nutrition was not used. It is concluded that all patients with significant gastrointestinal fistula should be given appropriate parenteral nutrition as their prime mode of therapy.


Jun 26, 2010·ANZ Journal of Surgery·D E GyorkiA G Heriot
Jul 1, 1986·The Proceedings of the Nutrition Society·D B Silk
Feb 14, 2002·JPEN. Journal of Parenteral and Enteral Nutrition·ASPEN Board of Directors and the Clinical Guidelines Task Force
Jun 29, 2006·The British Journal of Surgery·D A J LloydA C J Windsor
Apr 1, 1984·The British Journal of Surgery·P B McIntyreJ E Lennard-Jones
Feb 1, 1983·The Australian and New Zealand Journal of Surgery·G Ramsey-Stewart, A Shun
Oct 27, 2004·The British Journal of Surgery·P HollingtonA J Windsor

Related Concepts

Pathologic Fistula
Gastric Fistula
Cholera Infantum
Cholecystoduodenal Fistula
Parenteral Nutrition
Peritoneal Diseases
Postoperative Complications

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Neural Activity: Imaging

Imaging of neural activity in vivo has developed rapidly recently with the advancement of fluorescence microscopy, including new applications using miniaturized microscopes (miniscopes). This feed follows the progress in this growing field.

The Tendon Seed Network

Tendons are rich in the extracellular matrix and are abundant throughout the body providing essential roles including structure and mobility. The transcriptome of tendons is being compiled to understand the micro-anatomical functioning of tendons. Discover the latest research pertaining to the Tendon Seed Network here.

Myocardial Stunning

Myocardial stunning is a mechanical dysfunction that persists after reperfusion of previously ischemic tissue in the absence of irreversible damage including myocardial necrosis. Here is the latest research.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.


Incretins are metabolic hormones that stimulate a decrease in glucose levels in the blood and they have been implicated in glycemic regulation in the remission phase of type 1 diabetes. Here is the latest research.

Chromatin Regulation and Circadian Clocks

The circadian clock plays an important role in regulating transcriptional dynamics through changes in chromatin folding and remodelling. Discover the latest research on Chromatin Regulation and Circadian Clocks here.

Long COVID-19

“Long Covid-19” describes illness in patients who are reporting long-lasting effects of the SARS-CoV-19 infection, often long after they have recovered from acute Covid-19. Ongoing health issues often reported include low exercise tolerance and breathing difficulties, chronic tiredness, and mental health problems such as post-traumatic stress disorder and depression. This feed follows the latest research into Long Covid.

Spatio-Temporal Regulation of DNA Repair

DNA repair is a complex process regulated by several different classes of enzymes, including ligases, endonucleases, and polymerases. This feed focuses on the spatial and temporal regulation that accompanies DNA damage signaling and repair enzymes and processes.

Related Papers

The Australian and New Zealand Journal of Surgery
G A KuneJ Russell
Annales Chirurgiae Et Gynaecologiae
C Palnaes HansenO Olsen
Journal of the Royal Society of Medicine
J H Hobbiss, P F Schofield
Zhonghua yi xue za zhi = Chinese medical journal; Free China ed
F ChiangS I Liu
© 2021 Meta ULC. All rights reserved