The use of polydimethylsiloxane in the treatment of incontinence after radical prostatectomy

British Journal of Urology
T ColomboG Hubmer

Abstract

To report the results of transurethral submucosal injection therapy of polydimethylsiloxane (PDS) to treat incontinence after radical prostatectomy (RP). Since 1993, about 80 retropubic RPs have been carried out at our institution each year. Severe post-operative incontinence occurred in six patients, with a mean duration of incontinence after RP of 28 months. The pre-operative evaluation consisted of cysto-urethroscopy and urodynamics. Because we have no experience with artificial sphincter implantation, transurethral injection therapy was used to treat the post-operative incontinence, using PDS (vulcanized silicone rubber particles). This material has a mean particle size of 188 microns, providing stability of the material at the injection site. The six patients with severe post-operative incontinence were treated using injection therapy with PDS. After a mean follow up of 15.5 months, five patients, who suffered from day and night incontinence and required at least five pads per day, were dry after injection therapy. One patient improved significantly but still required two pads during the day, but was continent during the night; three patients required a second injection. A mean of 7.5 mL of PDS was used per patient and the...Continue Reading

Citations

Apr 12, 2003·Journal of Endourology·Timo KylmäläTeuvo L J Tammela
Oct 7, 2003·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Miguel CaballeroLucia Alòs
May 24, 2001·The Journal of Urology·J M GuysA Hautier
Mar 22, 2014·Korean journal of urology·Sin Woo LeeKyu-Sung Lee
Nov 14, 2000·Journal of Biomedical Materials Research·C SittelH E Eckel
Jul 20, 2019·Neurourology and Urodynamics·B ToiaT Greenwell
Mar 7, 2006·The Annals of Otology, Rhinology, and Laryngology·Christian SittelPeter K Plinkert

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