The use of sample genealogies for studying a selectively neutral m-loci model with recombination

Theoretical Population Biology
N L Kaplan, R R Hudson

Abstract

A selectively neutral m-loci model with recombination is studied. A general method is developed to calculate the variance of the number of segregating sites in samples of arbitrary size and the m-loci homozygosity. The method is based on properties of the genealogy of the sample rather than diffusion approximations. To demonstrate the scope of the method several calculations are presented.

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