The Use of the Angiosome Concept for Treating Infrapopliteal Critical Limb Ischemia through Interventional Therapy and Determining the Clinical Significance of Collateral Vessels

Annals of Vascular Surgery
Xiang-Tao ZhengGuan-Feng Yu

Abstract

The purpose of this study was to evaluate the clinical significance of the involvement of collateral vessels in interventional therapy based on the angiosome concept for infrapopliteal critical limb ischemia (CLI). We enrolled 486 patients with unilateral infrapopliteal CLI (Rutherford Stage 5 or 6) treated at 2 hospitals from January 2005 to December 2014. Using the angiosome concept, the patients were categorized into 3 groups: the direct revascularization (DR) group, the indirect revascularization through collaterals (IR-tc) group, and the indirect revascularization without collaterals (IR-wc) group. The data from 1 year of follow-up after the initial surgery were analyzed for all 3 groups. During the 1-year follow-up, the unhealed ulcer rate of the IR-wc group was significantly higher than that of the DR group (83.4% vs. 31.7%, P < 0.001) and the IR-tc group (83.4% vs. 34.8%, P < 0.001). Furthermore, the limb salvage rate of the IR-wc group was significantly lower than that of the DR group (70.4% vs. 89.2%, P < 0.001) and the IR-tc group (70.4% vs. 85.4%, P = 0.0013). However, there were no differences in the unhealed ulcer rate or the limb salvage rate between the DR group and the IR-tc group (31.7% vs. 34.8%, P = 0.096 an...Continue Reading

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Citations

Apr 20, 2017·Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists·Gagan D SinghEhrin J Armstrong
Nov 12, 2019·Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists·Vlad-Adrian AlexandrescuTommy Sinatra
Nov 28, 2019·Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists·Stavros SpiliopoulosAndreas Lazaris
Sep 12, 2020·The International Journal of Lower Extremity Wounds·Roberto FerraresiRobert G Frykberg
Oct 12, 2018·EFORT Open Reviews·Andreas F MavrogenisAndreas Lazaris

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