The use of tympanocentesis in the diagnosis and management of acute otitis media.

Current Infectious Disease Reports
M E Pichichero, Tracy Wright

Abstract

Acute otitis media (AOM), when associated with a bulging or full tympanic membrane, has a bacterial etiology in more than 90% of cases. Not infrequently, the organisms present express resistance mechanisms to commonly prescribed antibiotic therapy. Tympanocentesis is a procedure advocated by several national guidelines for use in selected patients not clinically responding to antimicrobial treatment. In this paper we discuss the use of tympanocentesis as a tool to track pathogen shifts and to guide antibiotic selection. We detail the indications for tympanocentesis, compare guidelines endorsing the procedure, and describe how to implement a technique for use in the primary care setting. The pros and cons of using tympanocentesis in clinical trial designs are also presented.

References

Jan 1, 1992·The Annals of Otology, Rhinology, and Laryngology·H FadenP L Ogra
Aug 1, 1968·Clinical Pediatrics·S E Stool
Apr 1, 1981·The Journal of Pediatrics·D W TeeleJ O Klein
Jul 1, 1981·Clinical Pediatrics·R H SchwartzW N Khan
Mar 1, 1995·The Pediatric Infectious Disease Journal·M E Pichichero, C L Pichichero
Mar 1, 1995·The Pediatric Infectious Disease Journal·M E Pichichero, C L Pichichero
Apr 1, 1997·The Pediatric Infectious Disease Journal·S L Block
Nov 5, 1998·The Pediatric Infectious Disease Journal·P GehannoP Berche
Jan 7, 1999·The Pediatric Infectious Disease Journal·E LeibovitzR Dagan
Sep 23, 2000·The Pediatric Infectious Disease Journal·M E Pichichero
Feb 15, 2001·The New England Journal of Medicine·J EskolaUNKNOWN Finnish Otitis Media Study Group
Oct 18, 2001·Archives of Pediatrics & Adolescent Medicine·M E Pichichero, M D Poole
Apr 5, 2002·Journal of the American Academy of Nurse Practitioners·A Sorrento, M E Pichichero
Jun 7, 2003·The Pediatric Infectious Disease Journal·Lolita PiglanskyRon Dagan
Oct 11, 2003·The Pediatric Infectious Disease Journal·Rosemary Johann-LiangJohn H Powers
May 4, 2004·Pediatrics·UNKNOWN American Academy of Pediatrics Subcommittee on Management of Acute Otitis Media
Sep 14, 2004·The Pediatric Infectious Disease Journal·Janet R Casey, Michael E Pichichero

❮ Previous
Next ❯

Citations

Jun 21, 2014·International Journal of Pediatric Otorhinolaryngology·Marie Gisselsson-Solen
Jun 4, 2014·Clinical and Experimental Immunology·D Verhoeven, M E Pichichero
Mar 30, 2018·Journal of Medical Microbiology·Yoko AdachiSatoshi Iwata
Jan 24, 2013·The Pediatric Infectious Disease Journal·Ellen R Wald, Gregory P DeMuri
May 26, 2018·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Ruggero LapennaGiampietro Ricci
Dec 26, 2015·JAAPA : Official Journal of the American Academy of Physician Assistants·Kate D Shand, Kristin Campe

❮ Previous
Next ❯

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.