The use of UK primary care databases in health technology assessments carried out by the National Institute for health and care excellence (NICE)

BMC Health Services Research
Thomas P LeahyCormac Sammon

Abstract

Real world evidence (RWE) is becoming more frequently used in technology appraisals (TAs). This study sought to explore the use and acceptance of evidence from primary care databases, a key source of RWE in the UK, in National Institute for Health and Care Excellence (NICE) technology assessments and to provide recommendations regarding their use in future submissions. A keyword search was conducted relating to the main primary care databases in the UK on the NICE website. All NICE TAs identified through this search were screened, assessed for duplication and information on the data source and the way the data was used in the submission were extracted. Comments by the evidence review group (ERG) and the appraisal committee were also extracted and reviewed. All data extraction was performed by two independent reviewers and all decisions were reached by consensus with an additional third reviewer. A total of 52 NICE TAs were identified, 47 used the General Practice Research Database /Clinical Practice Research Datalink (GPRD/CPRD) database, 10 used The Health Improvement Network (THIN) database and 3 used the QResearch databases. Data from primary care databases were used to support arguments regarding clinical need and current t...Continue Reading

References

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Citations

Jan 29, 2019·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Sanjay Gokhale, Sankalp Gokhale
Apr 3, 2020·Journal of Interprofessional Care·Mary LeeMaria Athina Martimianakis
Aug 19, 2020·Cancer Medicine·Marco Shiu Tsun LeungAmer Harky

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Software Mentioned

PRISMA
QResearch

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